Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption
Deep brain stimulation (DBS) pacemakers are sophisticated medical devices that deliver electrical signals to targeted areas of the brain via implanted electrodes, effectively regulating abnormal brain activity and relieving symptoms of treatment-resistant neurological disorders. However, proximity t...
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| Format: | Article |
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AIMS Press
2024-07-01
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| Series: | AIMS Bioengineering |
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| Online Access: | https://www.aimspress.com/article/doi/10.3934/bioeng.2024013 |
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| author | Baraa Chasib Mezher AL Kasar Shahab Khameneh Asl Hamed Asgharzadeh Seyed Jamaleddin Peighambardoust |
| author_facet | Baraa Chasib Mezher AL Kasar Shahab Khameneh Asl Hamed Asgharzadeh Seyed Jamaleddin Peighambardoust |
| author_sort | Baraa Chasib Mezher AL Kasar |
| collection | DOAJ |
| description | Deep brain stimulation (DBS) pacemakers are sophisticated medical devices that deliver electrical signals to targeted areas of the brain via implanted electrodes, effectively regulating abnormal brain activity and relieving symptoms of treatment-resistant neurological disorders. However, proximity to other electromagnetic equipment may introduce additional noise, which can be disruptive to individuals. To mitigate this issue, we propose a novel polymer-based nanocomposite for pacemakers for signal denoising. This research focused on the development and analysis of nanocomposites comprising polypropylene (PP) combined with montmorillonite nanoclay and graphene nanosheets (GNs). The nanocomposites were created by blending them through melting, using varying ratios of clay to GNs, with a total loading of 4 wt.%. This study focused on enhancing the signal-to-noise ratio for brain pacemakers by using nanocomposites. It investigated the noise reduction properties of PP nanocomposites, specifically in the outlet gate of the pacemaker. This research aimed to find the ideal ratio of clay to GNs in the PP matrix. X-ray diffraction (XRD) and differential scanning calorimetry (DSC) were conducted to analyze the crystalline structure and filler dispersion, as well as thermal behavior and filler–matrix interactions in the material. Scanning electron microscopy was employed to observe the dispersion of the nanofillers in the PP, and sound tube testing was conducted to evaluate the noise levels of the composites. The findings indicated that a porous structure of the nanocomposite with dispersed microspheres within the PP matrix and a long pathway facilitated increased dissipation of acoustic waves, making it suitable for denoising in brain pacemakers. Furthermore, the nanocomposite containing 2.75 wt.% of nanoclay and 1.25 wt.% of graphene components within the polypropylene matrix demonstrated a favorable signal-to-noise ratio compared to other evaluated nanocomposites. |
| format | Article |
| id | doaj-art-c7074ebd010b4eb4845f39b6faf9f052 |
| institution | Kabale University |
| issn | 2375-1495 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | AIMS Bioengineering |
| spelling | doaj-art-c7074ebd010b4eb4845f39b6faf9f0522025-01-24T01:28:36ZengAIMS PressAIMS Bioengineering2375-14952024-07-0111224126510.3934/bioeng.2024013Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorptionBaraa Chasib Mezher AL Kasar0Shahab Khameneh Asl1Hamed Asgharzadeh2Seyed Jamaleddin Peighambardoust3Department of Materials Engineering, Faculty of Mechanical Engineering, University of Tabriz, Tabriz 51666-14766, IranDepartment of Materials Engineering, Faculty of Mechanical Engineering, University of Tabriz, Tabriz 51666-14766, IranDepartment of Materials Engineering, Faculty of Mechanical Engineering, University of Tabriz, Tabriz 51666-14766, IranFaculty of Chemical and Petroleum Engineering, University of Tabriz, Tabriz 5166616471, IranDeep brain stimulation (DBS) pacemakers are sophisticated medical devices that deliver electrical signals to targeted areas of the brain via implanted electrodes, effectively regulating abnormal brain activity and relieving symptoms of treatment-resistant neurological disorders. However, proximity to other electromagnetic equipment may introduce additional noise, which can be disruptive to individuals. To mitigate this issue, we propose a novel polymer-based nanocomposite for pacemakers for signal denoising. This research focused on the development and analysis of nanocomposites comprising polypropylene (PP) combined with montmorillonite nanoclay and graphene nanosheets (GNs). The nanocomposites were created by blending them through melting, using varying ratios of clay to GNs, with a total loading of 4 wt.%. This study focused on enhancing the signal-to-noise ratio for brain pacemakers by using nanocomposites. It investigated the noise reduction properties of PP nanocomposites, specifically in the outlet gate of the pacemaker. This research aimed to find the ideal ratio of clay to GNs in the PP matrix. X-ray diffraction (XRD) and differential scanning calorimetry (DSC) were conducted to analyze the crystalline structure and filler dispersion, as well as thermal behavior and filler–matrix interactions in the material. Scanning electron microscopy was employed to observe the dispersion of the nanofillers in the PP, and sound tube testing was conducted to evaluate the noise levels of the composites. The findings indicated that a porous structure of the nanocomposite with dispersed microspheres within the PP matrix and a long pathway facilitated increased dissipation of acoustic waves, making it suitable for denoising in brain pacemakers. Furthermore, the nanocomposite containing 2.75 wt.% of nanoclay and 1.25 wt.% of graphene components within the polypropylene matrix demonstrated a favorable signal-to-noise ratio compared to other evaluated nanocomposites.https://www.aimspress.com/article/doi/10.3934/bioeng.2024013deep brain stimulationpolypropylene (pp)/clay/graphenenanocompositedenoising propertiesporous media |
| spellingShingle | Baraa Chasib Mezher AL Kasar Shahab Khameneh Asl Hamed Asgharzadeh Seyed Jamaleddin Peighambardoust Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption AIMS Bioengineering deep brain stimulation polypropylene (pp)/clay/graphene nanocomposite denoising properties porous media |
| title | Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption |
| title_full | Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption |
| title_fullStr | Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption |
| title_full_unstemmed | Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption |
| title_short | Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption |
| title_sort | denoising deep brain stimulation pacemaker signals with novel polymer based nanocomposites porous biomaterials for sound absorption |
| topic | deep brain stimulation polypropylene (pp)/clay/graphene nanocomposite denoising properties porous media |
| url | https://www.aimspress.com/article/doi/10.3934/bioeng.2024013 |
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