Paracetamol-induced hepatotoxicity in a malnourished patient: A case report

Acetaminophen, an analgesic and antipyretic with a favorable safety profile, is used globally. However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who dev...

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Bibliographic Details
Main Authors: Sudhanshu Shukla, Tejashree Sridhar, Jayasheela Siddalingayya Hiremath, Sanathkumar B. Nyamagoud, Viswanatha Agadi Hiremath Swamy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-04-01
Series:MGM Journal of Medical Sciences
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Online Access:https://doi.org/10.4103/mgmj.mgmj_88_24
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Summary:Acetaminophen, an analgesic and antipyretic with a favorable safety profile, is used globally. However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who developed severe hepatotoxicity attributed to the administration of paracetamol following right radical hemicolectomy. Despite the patient receiving paracetamol at a dosage below the recommended limit under medical supervision, he experienced a rapid deterioration in liver function, leading to a cascade of life-threatening complications. The intricate interplay between medication administration and patient-specific factors emphasizes the ongoing need for the medical community to evolve and optimize treatment strategies for improved patient outcomes.
ISSN:2347-7946
2347-7962