Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic study
Abstract Background Pyroptosis is a form of programmed cell death characterized by inflammasome activation and the release of inflammatory cytokines, which induce a strong immune response. Unlike apoptosis, pyroptosis can elicit potent immune stimulation, potentially playing a crucial role in anti-t...
Saved in:
| Main Authors: | Siyu Tao, Yunhao Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02421-6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Creation of an innovative diagnostic framework for hepatocellular carcinoma employing bioinformatics techniques focused on senescence-related and pyroptosis-related genes
by: Baixue Liu, et al.
Published: (2025-02-01) -
Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation
by: Yuan Yuan, et al.
Published: (2025-12-01) -
Identification of pyroptosis-associated miRNAs in the immunoscape and prognosis of hepatocellular carcinoma
by: Yuting Zheng, et al.
Published: (2024-12-01) -
Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing
by: Haoming Shen, et al.
Published: (2025-08-01) -
ATP6AP1 drives pyroptosis-mediated immune evasion in hepatocellular carcinoma: a machine learning-guided therapeutic target
by: Lei Tang, et al.
Published: (2025-04-01)