Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic study

Abstract Background Pyroptosis is a form of programmed cell death characterized by inflammasome activation and the release of inflammatory cytokines, which induce a strong immune response. Unlike apoptosis, pyroptosis can elicit potent immune stimulation, potentially playing a crucial role in anti-t...

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Bibliographic Details
Main Authors: Siyu Tao, Yunhao Yang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-02421-6
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