Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer

Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer

Abstract Objective Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinicopathological and molecular hallmarks that differentiate it from the more common invasive carcinoma—no special type (NST). Despite these differences, ILC and NST are treated...

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Main Authors: Susrutha Puthanmadhom Narayanan, Abdalla M. Wedn, Osama Shiraz Shah, Jian Chen, Daniel D. Brown, Priscilla F. McAuliffe, Steffi Oesterreich, Adrian V. Lee
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Breast Cancer Research
Subjects:
Invasive lobular cancer (ILC)
Invasive carcinoma—No Special Type (NST)
Protein Kinase A (PKA)
Cyclic AMP (cAMP)
CAMP Response Element Binding Protein (CREB)
Forskolin
Online Access:https://doi.org/10.1186/s13058-024-01900-y
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https://doi.org/10.1186/s13058-024-01900-y

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