Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could i...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2017/3578090 |
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| _version_ | 1832566571457839104 |
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| author | Jaime Cofre Eliana Abdelhay |
| author_facet | Jaime Cofre Eliana Abdelhay |
| author_sort | Jaime Cofre |
| collection | DOAJ |
| description | Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. Thus, this “cancer process” allows the harmonious and coherent construction of the embryo structural base, and its implementation as the embryonic process involves joint regulation of differentiation, proliferation, cell invasion, and migration, enabling the human being recreation of every generation. On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context. |
| format | Article |
| id | doaj-art-c68524589d7145f38b2d2cc6d344e22a |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-c68524589d7145f38b2d2cc6d344e22a2025-02-03T01:03:48ZengWileyThe Scientific World Journal2356-61401537-744X2017-01-01201710.1155/2017/35780903578090Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological PhenomenonJaime Cofre0Eliana Abdelhay1Laboratório de Embriologia Molecular e Câncer, Universidade Federal de Santa Catarina, Sala 313b, 88040-900 Florianópolis, SC, BrazilDivisão de Laboratórios do CEMO, Instituto Nacional do Câncer, Rio de Janeiro, RJ, BrazilDespite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. Thus, this “cancer process” allows the harmonious and coherent construction of the embryo structural base, and its implementation as the embryonic process involves joint regulation of differentiation, proliferation, cell invasion, and migration, enabling the human being recreation of every generation. On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context.http://dx.doi.org/10.1155/2017/3578090 |
| spellingShingle | Jaime Cofre Eliana Abdelhay Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon The Scientific World Journal |
| title | Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon |
| title_full | Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon |
| title_fullStr | Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon |
| title_full_unstemmed | Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon |
| title_short | Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon |
| title_sort | cancer is to embryology as mutation is to genetics hypothesis of the cancer as embryological phenomenon |
| url | http://dx.doi.org/10.1155/2017/3578090 |
| work_keys_str_mv | AT jaimecofre canceristoembryologyasmutationistogeneticshypothesisofthecancerasembryologicalphenomenon AT elianaabdelhay canceristoembryologyasmutationistogeneticshypothesisofthecancerasembryologicalphenomenon |