Inhibition of gamma-secretase activity without interfering in Notch signalling decreases inflammatory response in patients with cutaneous leishmaniasis

Cutaneous leishmaniasis (CL) patients present an exacerbated inflammatory response associated with tissue damage and ulcer development. Increasing numbers of patients have exhibited treatment failure, which remains not well understood. We hypothesized that adjuvant anti-inflammatory therapy would be...

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Bibliographic Details
Main Authors: Maurício T. Nascimento, Mônica Franca, Augusto M. Carvalho, Camila F. Amorim, Fábio Peixoto, Daniel Beiting, Phillip Scott, Edgar M. Carvalho, Lucas P. Carvalho
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
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Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1932608
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