Heterogeneous population dynamics and scaling laws near epidemic outbreaks

In this paper, we focus on the influence of heterogeneity and stochasticity of the population on thedynamical structure of a basic susceptible-infected-susceptible (SIS) model. Firstwe prove that, upon a suitable mathematical reformulation of the basic reproduction number, thehomogeneous system and...

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Main Authors: Andreas Widder, Christian Kuehn
Format: Article
Language:English
Published: AIMS Press 2016-06-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2016032
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author Andreas Widder
Christian Kuehn
author_facet Andreas Widder
Christian Kuehn
author_sort Andreas Widder
collection DOAJ
description In this paper, we focus on the influence of heterogeneity and stochasticity of the population on thedynamical structure of a basic susceptible-infected-susceptible (SIS) model. Firstwe prove that, upon a suitable mathematical reformulation of the basic reproduction number, thehomogeneous system and the heterogeneous system exhibit a completely analogous globalbehaviour. Then we consider noise terms to incorporate the fluctuation effects and therandom import of the disease into the population and analyse the influence of heterogeneityon warning signs for critical transitions (or tipping points). This theory shows that one maybe able to anticipate whether a bifurcation point is close before it happens. We use numericalsimulations of a stochastic fast-slow heterogeneous population SIS model and show various aspectsof heterogeneity have crucial influences on the scaling laws that are used as early-warningsigns for the homogeneous system. Thus, although the basic structural qualitative dynamicalproperties are the same for both systems, the quantitative features for epidemic predictionare expected to change and care has to be taken to interpret potential warning signs for diseaseoutbreaks correctly.
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spelling doaj-art-c67097fd9e2a49f6acb9744c222176922025-01-24T02:36:58ZengAIMS PressMathematical Biosciences and Engineering1551-00182016-06-011351093111810.3934/mbe.2016032Heterogeneous population dynamics and scaling laws near epidemic outbreaksAndreas Widder0Christian Kuehn1ORCOS, Institute of Statistics and Mathematical Methods in Economics, Vienna University of Technology, Wiedner Hauptstrasse 8, A-1040 ViennaFaculty of Mathematics, Technical University of Munich, Boltzmannstrasse 3, 85748 GarchingIn this paper, we focus on the influence of heterogeneity and stochasticity of the population on thedynamical structure of a basic susceptible-infected-susceptible (SIS) model. Firstwe prove that, upon a suitable mathematical reformulation of the basic reproduction number, thehomogeneous system and the heterogeneous system exhibit a completely analogous globalbehaviour. Then we consider noise terms to incorporate the fluctuation effects and therandom import of the disease into the population and analyse the influence of heterogeneityon warning signs for critical transitions (or tipping points). This theory shows that one maybe able to anticipate whether a bifurcation point is close before it happens. We use numericalsimulations of a stochastic fast-slow heterogeneous population SIS model and show various aspectsof heterogeneity have crucial influences on the scaling laws that are used as early-warningsigns for the homogeneous system. Thus, although the basic structural qualitative dynamicalproperties are the same for both systems, the quantitative features for epidemic predictionare expected to change and care has to be taken to interpret potential warning signs for diseaseoutbreaks correctly.https://www.aimspress.com/article/doi/10.3934/mbe.2016032warning signscritical transitiontranscritical bifurcationheterogeneous populationstochastic perturbationsis-modelreproduction number.epidemicstipping point
spellingShingle Andreas Widder
Christian Kuehn
Heterogeneous population dynamics and scaling laws near epidemic outbreaks
Mathematical Biosciences and Engineering
warning signs
critical transition
transcritical bifurcation
heterogeneous population
stochastic perturbation
sis-model
reproduction number.
epidemics
tipping point
title Heterogeneous population dynamics and scaling laws near epidemic outbreaks
title_full Heterogeneous population dynamics and scaling laws near epidemic outbreaks
title_fullStr Heterogeneous population dynamics and scaling laws near epidemic outbreaks
title_full_unstemmed Heterogeneous population dynamics and scaling laws near epidemic outbreaks
title_short Heterogeneous population dynamics and scaling laws near epidemic outbreaks
title_sort heterogeneous population dynamics and scaling laws near epidemic outbreaks
topic warning signs
critical transition
transcritical bifurcation
heterogeneous population
stochastic perturbation
sis-model
reproduction number.
epidemics
tipping point
url https://www.aimspress.com/article/doi/10.3934/mbe.2016032
work_keys_str_mv AT andreaswidder heterogeneouspopulationdynamicsandscalinglawsnearepidemicoutbreaks
AT christiankuehn heterogeneouspopulationdynamicsandscalinglawsnearepidemicoutbreaks