<i>Eugenia uniflora</i> Effects on the Depressive-like Behavior of MPTP-Exposed Female Rats: Apoptosis and α-Synuclein Modulation

<i>Eugenia uniflora</i> Effects on the Depressive-like Behavior of MPTP-Exposed Female Rats: Apoptosis and α-Synuclein Modulation

<b>Background:</b> Parkinson’s disease (PD) is a neurodegenerative disorder marked by motor deficits and non-motor symptoms, such as depression, which are associated with dopaminergic loss and α-synuclein aggregation in the brain. <b>Objectives:</b> This study investigated th...

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Main Authors: Anne Suély Pinto Savall, Jhuly Dorneles De Mello, Eduarda Monteiro Fidelis, Vandreza Cardoso Bortolotto, Mustafa Munir Mustafa Dahleh, Gustavo Petri Guerra, Marina Prigol, Robson Puntel, Jean Ramos Boldori, Cristiane Casagrande Denardin, Tuane Bazanella Sampaio, Simone Pinton
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Brain Sciences
Subjects:
Parkinson’s disease
apoptotic
Lewy bodies
Brazilian purple cherry
p-53/Bax/Bcl-2
intranasal MPTP
Online Access:https://www.mdpi.com/2076-3425/15/1/41
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