Shared clinical and immunologic features of mRNA vaccines: preliminary results from a comparative clinical study

Shared clinical and immunologic features of mRNA vaccines: preliminary results from a comparative clinical study

IntroductionClinical trials do not typically assess underlying molecular mechanisms of vaccine immunogenicity or reactogenicity. We evaluated the reactogenicity and immunogenicity of 4 mRNA vaccines and potential contributing mechanisms and identified shared and unique clinical and immunologic featu...

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Bibliographic Details
Main Authors: Carlos Fierro, Nelia Sanchez-Crespo, Daniel Makrinos, Weijie Zhang, Yanbo Sun, Poonam Rohilla, Bethany Girard, Abidemi Adeniji, Anthony DiPiazza, Robert Paris
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
mRNA vaccines
safety
immunogenicity
T cells
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1501275/full
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