Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali
Background. We performed 2 cross-sectional studies in Ménaka in the Northeastern Mali across 9 sites in different ecological settings: 4 sites have permanent ponds, 4 without ponds, and one (City of Ménaka) has a semipermanent pond. We enrolled 1328 subjects in May 2004 (hot dry season) and 1422 in...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/367160 |
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| author | Ousmane A. Koita Lansana Sangaré Hammadoun A. Sango Sounkalo Dao Naffet Keita Moussa Maiga Mamadou Mounkoro Zoumana Fané Abderrhamane S. Maiga Klénon Traoré Amadou Diallo D. J. Krogstad |
| author_facet | Ousmane A. Koita Lansana Sangaré Hammadoun A. Sango Sounkalo Dao Naffet Keita Moussa Maiga Mamadou Mounkoro Zoumana Fané Abderrhamane S. Maiga Klénon Traoré Amadou Diallo D. J. Krogstad |
| author_sort | Ousmane A. Koita |
| collection | DOAJ |
| description | Background. We performed 2 cross-sectional studies in Ménaka in the Northeastern Mali across 9 sites in different ecological settings: 4 sites have permanent ponds, 4 without ponds, and one (City of Ménaka) has a semipermanent pond. We enrolled 1328 subjects in May 2004 (hot dry season) and 1422 in February 2005 (cold dry season) after the rainy season. Objective. To examine the seasonality of malaria parasite prevalence in this dry northern part of Mali at the edge of the Sahara desert. Results. Slide prevalence was lower in hot dry than cold dry season (4.94 versus 6.85%, P=0.025). Gametocyte rate increased to 0.91% in February. Four species were identified. Plasmodium falciparum was most prevalent (74.13 and 63.72%). P. malariae increased from 9.38% to 22.54% in February. In contrast, prevalence of P. vivax was higher (10.31%) without seasonal variation. Smear positivity was associated with splenomegaly (P=0.007). Malaria remained stable in the villages with ponds (P=0.221); in contrast, prevalence varied between the 2 seasons in the villages without ponds (P=0.004). Conclusion. Malaria was mesoendemic; 4 species circulates with a seasonal fluctuation for Plasmodium falciparum. |
| format | Article |
| id | doaj-art-c6291c8209164dc7848ecd3b5baf8fd1 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-c6291c8209164dc7848ecd3b5baf8fd12025-02-03T05:47:52ZengWileyJournal of Tropical Medicine1687-96861687-96942012-01-01201210.1155/2012/367160367160Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern MaliOusmane A. Koita0Lansana Sangaré1Hammadoun A. Sango2Sounkalo Dao3Naffet Keita4Moussa Maiga5Mamadou Mounkoro6Zoumana Fané7Abderrhamane S. Maiga8Klénon Traoré9Amadou Diallo10D. J. Krogstad11Laboratoire de Biologie Moléculaire Appliquée, Faculté des Sciences et Techniques, Université de Bamako, BP 2191, Bamako, MaliLaboratoire de Biologie Moléculaire Appliquée, Faculté des Sciences et Techniques, Université de Bamako, BP 2191, Bamako, MaliDépartement d’Epidémiologie et de Santé Publique, Faculté de Médecine, Pharmacie et d’OdontoStomatologie, Université de Bamako, BP 1805, Bamako, MaliService des Maladies Infectieuses, Hôpital National du Point G, BP 1805, Bamako, MaliDirection Régionale de la Santé de Gao, Ministère de la Santé, BP 232, Gao, MaliService des Maladies Infectieuses, Hôpital National du Point G, BP 1805, Bamako, MaliLaboratoire de Biologie Moléculaire Appliquée, Faculté des Sciences et Techniques, Université de Bamako, BP 2191, Bamako, MaliFaculté des Langues des Arts et des Sciences Humaines, Université de Bamako, BP E 3637, Bamako, MaliInstitut National de Recherche en Santé Publique, BP 1771, Bamako, MaliFaculté des Langues des Arts et des Sciences Humaines, Université de Bamako, BP E 3637, Bamako, MaliLaboratoire de Biologie Moléculaire Appliquée, Faculté des Sciences et Techniques, Université de Bamako, BP 2191, Bamako, MaliDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USABackground. We performed 2 cross-sectional studies in Ménaka in the Northeastern Mali across 9 sites in different ecological settings: 4 sites have permanent ponds, 4 without ponds, and one (City of Ménaka) has a semipermanent pond. We enrolled 1328 subjects in May 2004 (hot dry season) and 1422 in February 2005 (cold dry season) after the rainy season. Objective. To examine the seasonality of malaria parasite prevalence in this dry northern part of Mali at the edge of the Sahara desert. Results. Slide prevalence was lower in hot dry than cold dry season (4.94 versus 6.85%, P=0.025). Gametocyte rate increased to 0.91% in February. Four species were identified. Plasmodium falciparum was most prevalent (74.13 and 63.72%). P. malariae increased from 9.38% to 22.54% in February. In contrast, prevalence of P. vivax was higher (10.31%) without seasonal variation. Smear positivity was associated with splenomegaly (P=0.007). Malaria remained stable in the villages with ponds (P=0.221); in contrast, prevalence varied between the 2 seasons in the villages without ponds (P=0.004). Conclusion. Malaria was mesoendemic; 4 species circulates with a seasonal fluctuation for Plasmodium falciparum.http://dx.doi.org/10.1155/2012/367160 |
| spellingShingle | Ousmane A. Koita Lansana Sangaré Hammadoun A. Sango Sounkalo Dao Naffet Keita Moussa Maiga Mamadou Mounkoro Zoumana Fané Abderrhamane S. Maiga Klénon Traoré Amadou Diallo D. J. Krogstad Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali Journal of Tropical Medicine |
| title | Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali |
| title_full | Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali |
| title_fullStr | Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali |
| title_full_unstemmed | Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali |
| title_short | Effect of Seasonality and Ecological Factors on the Prevalence of the Four Malaria Parasite Species in Northern Mali |
| title_sort | effect of seasonality and ecological factors on the prevalence of the four malaria parasite species in northern mali |
| url | http://dx.doi.org/10.1155/2012/367160 |
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