Structural basis of β-glucopyranoside salicin recognition by a human bitter taste GPCR

Structural basis of β-glucopyranoside salicin recognition by a human bitter taste GPCR

Summary: The human perception of bitterness is mediated by type 2 taste receptors (TAS2Rs), which recognize a broad array of bitter substances with distinct chemical properties. TAS2R16 exhibits a pronounced selectivity for β-glucoside-moiety-containing compounds, such as salicin from willow bark. H...

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Bibliographic Details
Main Authors: Xin Wang, Cui Zhou, Weizhen Ao, Lijie Wu, Yiran Wu, Weixiu Xu, Shenhui Liu, Qiwen Tan, Ling Wang, Fei Zhao, Junlin Liu, Yuan Pei, Suwen Zhao, Tian Hua
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725003754
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