Plasma proteomics-based risk scores for psoriasis prediction: a novel approach to early diagnosis

Plasma proteomics-based risk scores for psoriasis prediction: a novel approach to early diagnosis

IntroductionPsoriasis is a chronic immune-mediated inflammatory skin disease with a significant global burden. Current risk assessment lacks integration of proteomic data with genetic and clinical factors. This study aimed to develop a plasma proteomics-based risk score (ProtRS) to improve psoriasis...

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Main Authors: Siyu Wei, Zehong Yue, Chen Sun, Yuping Zou, Haiyan Chen, Junxian Tao, Jing Xu, Yuan Xu, Ning Wang, Yan Guo, Qinduo Ren, Chang Wang, Songlin Lu, Ye Ma, Yu Dong, Chen Zhang, Hongmei Sun, Guoping Tang, Fanwu Kong, Wenhua Lv, Zhenwei Shang, Mingming Zhang, Yongshuai Jiang, Hongchao Lyu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
psoriasis
plasma proteomics
LASSO
protein risk score model
population attributable fraction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1618805/full
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