Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy

Duchenne’s muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular and respiratory complications, as well as prol...

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Main Authors: Ahmed Abdelgawwad Wefki Abdelgawwad Shousha, Maria Sanfilippo, Antonio Sabba, Paolo Pinchera
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2014/680568
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author Ahmed Abdelgawwad Wefki Abdelgawwad Shousha
Maria Sanfilippo
Antonio Sabba
Paolo Pinchera
author_facet Ahmed Abdelgawwad Wefki Abdelgawwad Shousha
Maria Sanfilippo
Antonio Sabba
Paolo Pinchera
author_sort Ahmed Abdelgawwad Wefki Abdelgawwad Shousha
collection DOAJ
description Duchenne’s muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular and respiratory complications, as well as prolonged recovery from anesthesia. In this case report, we describe a 25-year-old male patient admitted for cholecystectomy under general anesthesia. We induced our anesthesia by oxygen, propofol, fentanyl, and rocuronium bromide. Maintenance was done by fentanyl, rocuronium bromide, sevoflurane, and O2. We report in this case the safety use of sugammadex to antagonize the neuromuscular block and rapid recovery in such category of patients.
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series Case Reports in Anesthesiology
spelling doaj-art-c604dfc11f4d48e8a608ca5bc001391a2025-02-03T05:58:44ZengWileyCase Reports in Anesthesiology2090-63822090-63902014-01-01201410.1155/2014/680568680568Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular DystrophyAhmed Abdelgawwad Wefki Abdelgawwad Shousha0Maria Sanfilippo1Antonio Sabba2Paolo Pinchera3Department of Anesthesiology and Intensive Care, Sapienza University, Viale del policlinico 155, 00161 Rome, ItalyDepartment of Anesthesiology and Intensive Care, Sapienza University, Viale del policlinico 155, 00161 Rome, ItalyDepartment of Anesthesiology and Intensive Care, Sapienza University, Viale del policlinico 155, 00161 Rome, ItalyDepartment of Anesthesiology and Intensive Care, Sapienza University, Viale del policlinico 155, 00161 Rome, ItalyDuchenne’s muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular and respiratory complications, as well as prolonged recovery from anesthesia. In this case report, we describe a 25-year-old male patient admitted for cholecystectomy under general anesthesia. We induced our anesthesia by oxygen, propofol, fentanyl, and rocuronium bromide. Maintenance was done by fentanyl, rocuronium bromide, sevoflurane, and O2. We report in this case the safety use of sugammadex to antagonize the neuromuscular block and rapid recovery in such category of patients.http://dx.doi.org/10.1155/2014/680568
spellingShingle Ahmed Abdelgawwad Wefki Abdelgawwad Shousha
Maria Sanfilippo
Antonio Sabba
Paolo Pinchera
Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
Case Reports in Anesthesiology
title Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_full Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_fullStr Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_full_unstemmed Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_short Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_sort sugammadex and reversal of neuromuscular block in adult patient with duchenne muscular dystrophy
url http://dx.doi.org/10.1155/2014/680568
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