Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study

One laboratory-based and two non-laboratory-based models with and without blood pressure measures are developed based on data of 14815 men and 16617 women aged 25–64 years. During the followup 1134 men and 566 women developed coronary heart disease (CHD). The area under the receiver operating charac...

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Main Authors: Qing Qiao, Tiina Laatikainen, Weiguo Gao, Janne Pitkäniemi, Erkki Vartiainen
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2011/823782
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author Qing Qiao
Tiina Laatikainen
Weiguo Gao
Janne Pitkäniemi
Erkki Vartiainen
author_facet Qing Qiao
Tiina Laatikainen
Weiguo Gao
Janne Pitkäniemi
Erkki Vartiainen
author_sort Qing Qiao
collection DOAJ
description One laboratory-based and two non-laboratory-based models with and without blood pressure measures are developed based on data of 14815 men and 16617 women aged 25–64 years. During the followup 1134 men and 566 women developed coronary heart disease (CHD). The area under the receiver operating characteristic curve (95% CI) for prediction of CHD incidence was 0.823 (0.807–0.839) for the laboratory-based model, 0.808 (0.791–0.824) and 0.803 (0.787–0.820) for the non-laboratory-based models with and without systolic blood pressure in men (P<0.01 for overall comparison), and 0.878 (0.856–0.901), 0.871 (0.848–0.894), and 0.864 (0.840–0.887), respectively, in women (P<0.01). The predicted rates matched well with the observed ones (P>0.10). Compared with the model without blood pressure, the non-laboratory-based model with blood pressure tended to reclassify individuals into the higher risk categories for both event and nonevent groups in both genders. The study concludes the predictive property of the non-laboratory-based models are good.
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institution Kabale University
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series International Journal of Vascular Medicine
spelling doaj-art-c5faa065c0594f4cb129964e220018ff2025-02-03T06:45:57ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322011-01-01201110.1155/2011/823782823782Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK StudyQing Qiao0Tiina Laatikainen1Weiguo Gao2Janne Pitkäniemi3Erkki Vartiainen4Department of Public Health, University of Helsinki, PL41 Mannerheimintie 172, 00014 Helsinki, FinlandDepartment of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, FinlandDepartment of Public Health, University of Helsinki, PL41 Mannerheimintie 172, 00014 Helsinki, FinlandDepartment of Public Health, University of Helsinki, PL41 Mannerheimintie 172, 00014 Helsinki, FinlandDepartment of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, FinlandOne laboratory-based and two non-laboratory-based models with and without blood pressure measures are developed based on data of 14815 men and 16617 women aged 25–64 years. During the followup 1134 men and 566 women developed coronary heart disease (CHD). The area under the receiver operating characteristic curve (95% CI) for prediction of CHD incidence was 0.823 (0.807–0.839) for the laboratory-based model, 0.808 (0.791–0.824) and 0.803 (0.787–0.820) for the non-laboratory-based models with and without systolic blood pressure in men (P<0.01 for overall comparison), and 0.878 (0.856–0.901), 0.871 (0.848–0.894), and 0.864 (0.840–0.887), respectively, in women (P<0.01). The predicted rates matched well with the observed ones (P>0.10). Compared with the model without blood pressure, the non-laboratory-based model with blood pressure tended to reclassify individuals into the higher risk categories for both event and nonevent groups in both genders. The study concludes the predictive property of the non-laboratory-based models are good.http://dx.doi.org/10.1155/2011/823782
spellingShingle Qing Qiao
Tiina Laatikainen
Weiguo Gao
Janne Pitkäniemi
Erkki Vartiainen
Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
International Journal of Vascular Medicine
title Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
title_full Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
title_fullStr Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
title_full_unstemmed Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
title_short Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
title_sort layperson oriented versus clinical based models for assessing 10 year incidence of coronary heart disease national finrisk study
url http://dx.doi.org/10.1155/2011/823782
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