Investigation of the osteogenic effects of ICA and ICSII on rat bone marrow mesenchymal stem cells

Investigation of the osteogenic effects of ICA and ICSII on rat bone marrow mesenchymal stem cells

Abstract Icariin (ICA) serves as the primary biologically active compound in traditional Chinese medicine Epimedium, while Icariside II (ICSII) represents one of its gastrointestinal metabolites. Although ICA and ICSII have demonstrated osteogenic differentiation- promoting effects on BMSCs, there i...

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Bibliographic Details
Main Authors: Zhangshun Yao, Weixiang Huang, Yan Yang, Leiyan Zou, Yunpeng Zhang, Jing Zhang, Guangming Luo
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-86501-1
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