Changes in donor lymphocyte infusion for relapsed patients post-hematopoietic stem cell transplantation: a 30-year single-center experience

Changes in donor lymphocyte infusion for relapsed patients post-hematopoietic stem cell transplantation: a 30-year single-center experience

IntroductionDonor lymphocyte infusion (DLI) is a therapeutic approach for relapse after hematopoietic stem cell transplantation (HSCT). Despite their reported efficacy, the evolution of DLI practices over time remains underexplored.MethodsThis study provided a comprehensive analysis of DLI strategie...

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Main Authors: Yusuke Uchibori, Shuhei Kurosawa, Yuho Najima, Kyoko Haraguchi, Daichi Sadato, Chizuko Hirama, Yasutaka Sadaga, Kaori Kondo, Chika Kato, Satoshi Sakai, Yasuhiro Kambara, Fumihiko Ouchi, Masashi Shimabukuro, Atsushi Jinguji, Naoki Shingai, Takashi Toya, Hiroaki Shimizu, Takeshi Kobayashi, Hironori Harada, Yuka Harada, Yoshiki Okuyama, Noriko Doki
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
donor lymphocyte infusion
hematopoietic stem cell transplantation
refined disease risk index
acute graft-versus-host disease
acute myeloid leukemia
myelodysplastic syndromes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1521895/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1521895/full

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