Sciellin inhibits senescence and promotes pancreatic cancer progress by activating the notch signaling pathway
Abstract Pancreatic cancer (PC) incidence is increasing annually globally, and the five-year survival rate of patients with PC is approximately 10%. Cellular senescence is a regulatory mechanism against cancer that prevents tumor development by inhibiting the proliferation of damaged or abnormal cel...
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| Main Authors: | Changhao Wu, Dan Luo, Binbin Shi, Shiyu Chen, Chengyi Sun, Zhiwei He, Chao Yu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-88265-0 |
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