Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine
This study aimed at creation of a few new heterocyclic compounds that include sulfur and nitrogen atoms. Also, some chalcones, thiazolidine and Schiff base derivatives have been prepared. The spectroscopic data (IR, 1Hand 13C-NMR) have verified the structure of the produced molecules. Interesting fi...
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Serbian Chemical Society
2024-01-01
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Series: | Journal of the Serbian Chemical Society |
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Online Access: | https://doiserbia.nb.rs/img/doi/0352-5139/2024/0352-51392400067A.pdf |
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author | Aziz Hadil S. Al-Araj Intisar Q.M. Abdul-Raheem Linda R. Ahmed Amena A. |
author_facet | Aziz Hadil S. Al-Araj Intisar Q.M. Abdul-Raheem Linda R. Ahmed Amena A. |
author_sort | Aziz Hadil S. |
collection | DOAJ |
description | This study aimed at creation of a few new heterocyclic compounds that include sulfur and nitrogen atoms. Also, some chalcones, thiazolidine and Schiff base derivatives have been prepared. The spectroscopic data (IR, 1Hand 13C-NMR) have verified the structure of the produced molecules. Interesting findings were obtained when several synthetic substances were physiologically tested against a range of pathogenic Gram-positive and Gram-negative bacteria. |
format | Article |
id | doaj-art-c5aa7257c12f44aaa80f74a1f214026f |
institution | Kabale University |
issn | 0352-5139 1820-7421 |
language | English |
publishDate | 2024-01-01 |
publisher | Serbian Chemical Society |
record_format | Article |
series | Journal of the Serbian Chemical Society |
spelling | doaj-art-c5aa7257c12f44aaa80f74a1f214026f2025-01-30T06:45:49ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212024-01-0189111401141010.2298/JSC230813067A0352-51392400067ASynthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidineAziz Hadil S.0https://orcid.org/0000-0003-0391-4513Al-Araj Intisar Q.M.1https://orcid.org/0000-0003-1702-1062Abdul-Raheem Linda R.2https://orcid.org/0000-0002-6649-9786Ahmed Amena A.3https://orcid.org/0000-0003-3153-071XChemistry Department, College of Education for Pure Sciences, University of Mosul, Mosul, IraqChemistry Department, College of Education for Pure Sciences, University of Mosul, Mosul, IraqChemistry Department, College of Education for Pure Sciences, University of Mosul, Mosul, IraqChemistry Department, College of Education for Pure Sciences, University of Mosul, Mosul, IraqThis study aimed at creation of a few new heterocyclic compounds that include sulfur and nitrogen atoms. Also, some chalcones, thiazolidine and Schiff base derivatives have been prepared. The spectroscopic data (IR, 1Hand 13C-NMR) have verified the structure of the produced molecules. Interesting findings were obtained when several synthetic substances were physiologically tested against a range of pathogenic Gram-positive and Gram-negative bacteria.https://doiserbia.nb.rs/img/doi/0352-5139/2024/0352-51392400067A.pdfthiazolidinechalconesschiff basescyclizationpathogenic bacteria |
spellingShingle | Aziz Hadil S. Al-Araj Intisar Q.M. Abdul-Raheem Linda R. Ahmed Amena A. Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine Journal of the Serbian Chemical Society thiazolidine chalcones schiff bases cyclization pathogenic bacteria |
title | Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine |
title_full | Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine |
title_fullStr | Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine |
title_full_unstemmed | Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine |
title_short | Synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine |
title_sort | synthesis and biological evaluation of some new heterocyclic derivatives from substituted thiopyrimidine |
topic | thiazolidine chalcones schiff bases cyclization pathogenic bacteria |
url | https://doiserbia.nb.rs/img/doi/0352-5139/2024/0352-51392400067A.pdf |
work_keys_str_mv | AT azizhadils synthesisandbiologicalevaluationofsomenewheterocyclicderivativesfromsubstitutedthiopyrimidine AT alarajintisarqm synthesisandbiologicalevaluationofsomenewheterocyclicderivativesfromsubstitutedthiopyrimidine AT abdulraheemlindar synthesisandbiologicalevaluationofsomenewheterocyclicderivativesfromsubstitutedthiopyrimidine AT ahmedamenaa synthesisandbiologicalevaluationofsomenewheterocyclicderivativesfromsubstitutedthiopyrimidine |