Multidrug Resistant <i>Pseudomonas aeruginosa</i> in Clinical Settings: A Review of Resistance Mechanisms and Treatment Strategies

<i>Pseudomonas aeruginosa</i> is causing increasing concern among clinicians due to its high mortality and resistance rates. This bacterium is responsible for various infections, especially in hospital settings, affecting some of the most vulnerable patients. <i>Pseudomonas aerugin...

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Bibliographic Details
Main Authors: Beth Schwartz, Katherine Klamer, Justin Zimmerman, Pramodini B. Kale-Pradhan, Ashish Bhargava
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pathogens
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Online Access:https://www.mdpi.com/2076-0817/13/11/975
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Summary:<i>Pseudomonas aeruginosa</i> is causing increasing concern among clinicians due to its high mortality and resistance rates. This bacterium is responsible for various infections, especially in hospital settings, affecting some of the most vulnerable patients. <i>Pseudomonas aeruginosa</i> has developed resistance through multiple mechanisms, making treatment challenging. Diagnostic techniques are evolving, with rapid testing systems providing results within 4–6 h. New antimicrobial agents are continuously being developed, offering potential solutions to these complex clinical decisions. This article provides a review of the epidemiology, at-risk populations, resistance mechanisms, and diagnostic and treatment options for <i>Pseudomonas aeruginosa</i>.
ISSN:2076-0817