Spiradenoma: A Case Report and Review of the Literature

<b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a pa...

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Main Authors: Jia-Ying Chang, Yen-Chang Chen, Dah-Ching Ding
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/2/173
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author Jia-Ying Chang
Yen-Chang Chen
Dah-Ching Ding
author_facet Jia-Ying Chang
Yen-Chang Chen
Dah-Ching Ding
author_sort Jia-Ying Chang
collection DOAJ
description <b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a palpable lesion in the suprapubic region that had been there for 20 years and had become enlarged over the past 2 months. Physical examination revealed a firm, non-tender, subcutaneous mass, approximately 2 cm in size, in the right pubic region. Ultrasound revealed a hypoechoic, heterogeneous lesion with a well-defined border, measuring 2.37 × 0.94 × 1.67 cm, without hypervascularity. Therefore, the patient underwent excision of the subcutaneous tumor. The pathology report confirmed the diagnosis of spiradenoma of the pubis. Histochemistry showed that the inner luminal cells were positive for CK7, and the outer basaloid cells were positive for p63. CD56 and CD117 were focally positive. <b>Conclusions:</b> With an accurate diagnosis and appropriate surgical excision, the prognosis for spiradenoma is generally excellent. However, a long-term follow-up is advisable.
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spelling doaj-art-c57671cd03144a55a384dac2dcd69cf62025-01-24T13:28:59ZengMDPI AGDiagnostics2075-44182025-01-0115217310.3390/diagnostics15020173Spiradenoma: A Case Report and Review of the LiteratureJia-Ying Chang0Yen-Chang Chen1Dah-Ching Ding2Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 970, TaiwanDivision of Digital Pathology, Department of Anatomical Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 970, Taiwan<b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a palpable lesion in the suprapubic region that had been there for 20 years and had become enlarged over the past 2 months. Physical examination revealed a firm, non-tender, subcutaneous mass, approximately 2 cm in size, in the right pubic region. Ultrasound revealed a hypoechoic, heterogeneous lesion with a well-defined border, measuring 2.37 × 0.94 × 1.67 cm, without hypervascularity. Therefore, the patient underwent excision of the subcutaneous tumor. The pathology report confirmed the diagnosis of spiradenoma of the pubis. Histochemistry showed that the inner luminal cells were positive for CK7, and the outer basaloid cells were positive for p63. CD56 and CD117 were focally positive. <b>Conclusions:</b> With an accurate diagnosis and appropriate surgical excision, the prognosis for spiradenoma is generally excellent. However, a long-term follow-up is advisable.https://www.mdpi.com/2075-4418/15/2/173spiradenomaskin adnexasubcutaneousCK7surgical excision
spellingShingle Jia-Ying Chang
Yen-Chang Chen
Dah-Ching Ding
Spiradenoma: A Case Report and Review of the Literature
Diagnostics
spiradenoma
skin adnexa
subcutaneous
CK7
surgical excision
title Spiradenoma: A Case Report and Review of the Literature
title_full Spiradenoma: A Case Report and Review of the Literature
title_fullStr Spiradenoma: A Case Report and Review of the Literature
title_full_unstemmed Spiradenoma: A Case Report and Review of the Literature
title_short Spiradenoma: A Case Report and Review of the Literature
title_sort spiradenoma a case report and review of the literature
topic spiradenoma
skin adnexa
subcutaneous
CK7
surgical excision
url https://www.mdpi.com/2075-4418/15/2/173
work_keys_str_mv AT jiayingchang spiradenomaacasereportandreviewoftheliterature
AT yenchangchen spiradenomaacasereportandreviewoftheliterature
AT dahchingding spiradenomaacasereportandreviewoftheliterature