Spiradenoma: A Case Report and Review of the Literature
<b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a pa...
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2025-01-01
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author | Jia-Ying Chang Yen-Chang Chen Dah-Ching Ding |
author_facet | Jia-Ying Chang Yen-Chang Chen Dah-Ching Ding |
author_sort | Jia-Ying Chang |
collection | DOAJ |
description | <b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a palpable lesion in the suprapubic region that had been there for 20 years and had become enlarged over the past 2 months. Physical examination revealed a firm, non-tender, subcutaneous mass, approximately 2 cm in size, in the right pubic region. Ultrasound revealed a hypoechoic, heterogeneous lesion with a well-defined border, measuring 2.37 × 0.94 × 1.67 cm, without hypervascularity. Therefore, the patient underwent excision of the subcutaneous tumor. The pathology report confirmed the diagnosis of spiradenoma of the pubis. Histochemistry showed that the inner luminal cells were positive for CK7, and the outer basaloid cells were positive for p63. CD56 and CD117 were focally positive. <b>Conclusions:</b> With an accurate diagnosis and appropriate surgical excision, the prognosis for spiradenoma is generally excellent. However, a long-term follow-up is advisable. |
format | Article |
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institution | Kabale University |
issn | 2075-4418 |
language | English |
publishDate | 2025-01-01 |
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spelling | doaj-art-c57671cd03144a55a384dac2dcd69cf62025-01-24T13:28:59ZengMDPI AGDiagnostics2075-44182025-01-0115217310.3390/diagnostics15020173Spiradenoma: A Case Report and Review of the LiteratureJia-Ying Chang0Yen-Chang Chen1Dah-Ching Ding2Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 970, TaiwanDivision of Digital Pathology, Department of Anatomical Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 970, Taiwan<b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a palpable lesion in the suprapubic region that had been there for 20 years and had become enlarged over the past 2 months. Physical examination revealed a firm, non-tender, subcutaneous mass, approximately 2 cm in size, in the right pubic region. Ultrasound revealed a hypoechoic, heterogeneous lesion with a well-defined border, measuring 2.37 × 0.94 × 1.67 cm, without hypervascularity. Therefore, the patient underwent excision of the subcutaneous tumor. The pathology report confirmed the diagnosis of spiradenoma of the pubis. Histochemistry showed that the inner luminal cells were positive for CK7, and the outer basaloid cells were positive for p63. CD56 and CD117 were focally positive. <b>Conclusions:</b> With an accurate diagnosis and appropriate surgical excision, the prognosis for spiradenoma is generally excellent. However, a long-term follow-up is advisable.https://www.mdpi.com/2075-4418/15/2/173spiradenomaskin adnexasubcutaneousCK7surgical excision |
spellingShingle | Jia-Ying Chang Yen-Chang Chen Dah-Ching Ding Spiradenoma: A Case Report and Review of the Literature Diagnostics spiradenoma skin adnexa subcutaneous CK7 surgical excision |
title | Spiradenoma: A Case Report and Review of the Literature |
title_full | Spiradenoma: A Case Report and Review of the Literature |
title_fullStr | Spiradenoma: A Case Report and Review of the Literature |
title_full_unstemmed | Spiradenoma: A Case Report and Review of the Literature |
title_short | Spiradenoma: A Case Report and Review of the Literature |
title_sort | spiradenoma a case report and review of the literature |
topic | spiradenoma skin adnexa subcutaneous CK7 surgical excision |
url | https://www.mdpi.com/2075-4418/15/2/173 |
work_keys_str_mv | AT jiayingchang spiradenomaacasereportandreviewoftheliterature AT yenchangchen spiradenomaacasereportandreviewoftheliterature AT dahchingding spiradenomaacasereportandreviewoftheliterature |