Adult Dermatomyositis with Bleeding Ulcer in the Pharynx
Dermatomyositis (DM) is one of the idiopathic inflammatory myopathies caused by complement-mediated vasculopathy or vasculitis in the muscle. Although the gastrointestinal (GI) mucosa has been reported to be involved as a result of vasculitis or vasculopathy, ulceration in the pharynx is a rare mani...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2014/854841 |
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| author | Junko Kusano Yuka Takahashi Yoshikata Misaki Norihiko Murai |
| author_facet | Junko Kusano Yuka Takahashi Yoshikata Misaki Norihiko Murai |
| author_sort | Junko Kusano |
| collection | DOAJ |
| description | Dermatomyositis (DM) is one of the idiopathic inflammatory myopathies caused by complement-mediated vasculopathy or vasculitis in the muscle. Although the gastrointestinal (GI) mucosa has been reported to be involved as a result of vasculitis or vasculopathy, ulceration in the pharynx is a rare manifestation of DM. A 54-year-old woman complaining of muscle weakness in the extremities, low-grade fever, and dysphagia was diagnosed as having DM. Despite medical treatment with corticosteroids and immunosuppressive agents, her DM progressed rapidly, leading to exacerbation of the dysphagia. About 3 weeks after undergoing tracheostomy as a preventive measure against aspiration, the patient developed intractable respiratory tract hemorrhage. Repeated laryngoendoscopy revealed a bleeding ulceration in the pharynx that required hemostasis with electric cautery under general anesthesia. No bleeding recurred thereafter. Histopathologically, the pharynx exhibited nonspecific inflammatory cell infiltration in the muscle tissue. This rare manifestation may be considered in cases of DM with unexplainable airway bleeding. |
| format | Article |
| id | doaj-art-c565c532a1904519941ef31124a70932 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-c565c532a1904519941ef31124a709322025-02-03T06:04:58ZengWileyCase Reports in Otolaryngology2090-67652090-67732014-01-01201410.1155/2014/854841854841Adult Dermatomyositis with Bleeding Ulcer in the PharynxJunko Kusano0Yuka Takahashi1Yoshikata Misaki2Norihiko Murai3Department of Otolaryngology, Kyoto-Katsura Hospital, Yamada Hirao-cho 17, Nishikyo-ku, Kyoto 615 8256, JapanDepartment of Otolaryngology, Kyoto-Katsura Hospital, Yamada Hirao-cho 17, Nishikyo-ku, Kyoto 615 8256, JapanDepartment of Rheumatology, Kyoto-Katsura Hospital, Yamada Hirao-cho 17, Nishikyo-ku, Kyoto 615 8256, JapanDepartment of Otolaryngology, Kyoto-Katsura Hospital, Yamada Hirao-cho 17, Nishikyo-ku, Kyoto 615 8256, JapanDermatomyositis (DM) is one of the idiopathic inflammatory myopathies caused by complement-mediated vasculopathy or vasculitis in the muscle. Although the gastrointestinal (GI) mucosa has been reported to be involved as a result of vasculitis or vasculopathy, ulceration in the pharynx is a rare manifestation of DM. A 54-year-old woman complaining of muscle weakness in the extremities, low-grade fever, and dysphagia was diagnosed as having DM. Despite medical treatment with corticosteroids and immunosuppressive agents, her DM progressed rapidly, leading to exacerbation of the dysphagia. About 3 weeks after undergoing tracheostomy as a preventive measure against aspiration, the patient developed intractable respiratory tract hemorrhage. Repeated laryngoendoscopy revealed a bleeding ulceration in the pharynx that required hemostasis with electric cautery under general anesthesia. No bleeding recurred thereafter. Histopathologically, the pharynx exhibited nonspecific inflammatory cell infiltration in the muscle tissue. This rare manifestation may be considered in cases of DM with unexplainable airway bleeding.http://dx.doi.org/10.1155/2014/854841 |
| spellingShingle | Junko Kusano Yuka Takahashi Yoshikata Misaki Norihiko Murai Adult Dermatomyositis with Bleeding Ulcer in the Pharynx Case Reports in Otolaryngology |
| title | Adult Dermatomyositis with Bleeding Ulcer in the Pharynx |
| title_full | Adult Dermatomyositis with Bleeding Ulcer in the Pharynx |
| title_fullStr | Adult Dermatomyositis with Bleeding Ulcer in the Pharynx |
| title_full_unstemmed | Adult Dermatomyositis with Bleeding Ulcer in the Pharynx |
| title_short | Adult Dermatomyositis with Bleeding Ulcer in the Pharynx |
| title_sort | adult dermatomyositis with bleeding ulcer in the pharynx |
| url | http://dx.doi.org/10.1155/2014/854841 |
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