Viscoelastic Haemostatic Assays in Cardiovascular Critical Care

The initiation and management of anticoagulation is a fundamental practice for a wide variety of indications in cardiovascular critical care, including the management of patients with acute MI, stroke prevention in patients with AF or mechanical valves, as well as the prevention of device thrombosis...

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Main Authors: Aniket S Rali, Ahmed M Salem, Melat Gebre, Taylor M Garies, Siva Taduru, Arthur W Bracey
Format: Article
Language:English
Published: Radcliffe Medical Media 2021-02-01
Series:Cardiac Failure Review
Online Access:https://www.cfrjournal.com/articles/viscoelastic-haemostatic-assays-cardiovascular-critical-care
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author Aniket S Rali
Ahmed M Salem
Melat Gebre
Taylor M Garies
Siva Taduru
Arthur W Bracey
author_facet Aniket S Rali
Ahmed M Salem
Melat Gebre
Taylor M Garies
Siva Taduru
Arthur W Bracey
author_sort Aniket S Rali
collection DOAJ
description The initiation and management of anticoagulation is a fundamental practice for a wide variety of indications in cardiovascular critical care, including the management of patients with acute MI, stroke prevention in patients with AF or mechanical valves, as well as the prevention of device thrombosis and thromboembolic events with the use of mechanical circulatory support and ventricular assist devices. The frequent use of antiplatelet and anticoagulation therapy, in addition to the presence of concomitant conditions that may lead to a propensity to bleed, such as renal and liver dysfunction, present unique challenges. The use of viscoelastic haemostatic assays provides an additional tool allowing clinicians to strike a delicate balance of attaining adequate anticoagulation while minimising the risk of bleeding complications. In this review, the authors discuss the role that viscoelastic haemostatic assay plays in cardiac populations (including cardiac surgery, heart transplantation, extracorporeal membrane oxygenation, acute coronary syndrome and left ventricular assist devices), and identify areas in need of further study.
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issn 2057-7540
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publishDate 2021-02-01
publisher Radcliffe Medical Media
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series Cardiac Failure Review
spelling doaj-art-c564d77b82794e2784fb8683204eb9c62025-08-20T02:39:22ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592021-02-01710.15420/cfr.2020.22Viscoelastic Haemostatic Assays in Cardiovascular Critical CareAniket S Rali0Ahmed M Salem1Melat Gebre2Taylor M Garies3Siva Taduru4Arthur W Bracey5Division of Cardiovascular Medicine, Vanderbilt University Medical Centre, Nashville, Tennessee, USDivision of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, Texas, USDepartment of Anaesthesiology, Emory University School of Medicine, Atlanta, Georgia, USDepartment of Nursing, Vanderbilt University Medical Centre, Nashville, Tennessee, USDepartment of Cardiovascular Diseases, University of Kansas Medical Centre, Kansas City, Kansas, USDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USThe initiation and management of anticoagulation is a fundamental practice for a wide variety of indications in cardiovascular critical care, including the management of patients with acute MI, stroke prevention in patients with AF or mechanical valves, as well as the prevention of device thrombosis and thromboembolic events with the use of mechanical circulatory support and ventricular assist devices. The frequent use of antiplatelet and anticoagulation therapy, in addition to the presence of concomitant conditions that may lead to a propensity to bleed, such as renal and liver dysfunction, present unique challenges. The use of viscoelastic haemostatic assays provides an additional tool allowing clinicians to strike a delicate balance of attaining adequate anticoagulation while minimising the risk of bleeding complications. In this review, the authors discuss the role that viscoelastic haemostatic assay plays in cardiac populations (including cardiac surgery, heart transplantation, extracorporeal membrane oxygenation, acute coronary syndrome and left ventricular assist devices), and identify areas in need of further study.https://www.cfrjournal.com/articles/viscoelastic-haemostatic-assays-cardiovascular-critical-care
spellingShingle Aniket S Rali
Ahmed M Salem
Melat Gebre
Taylor M Garies
Siva Taduru
Arthur W Bracey
Viscoelastic Haemostatic Assays in Cardiovascular Critical Care
Cardiac Failure Review
title Viscoelastic Haemostatic Assays in Cardiovascular Critical Care
title_full Viscoelastic Haemostatic Assays in Cardiovascular Critical Care
title_fullStr Viscoelastic Haemostatic Assays in Cardiovascular Critical Care
title_full_unstemmed Viscoelastic Haemostatic Assays in Cardiovascular Critical Care
title_short Viscoelastic Haemostatic Assays in Cardiovascular Critical Care
title_sort viscoelastic haemostatic assays in cardiovascular critical care
url https://www.cfrjournal.com/articles/viscoelastic-haemostatic-assays-cardiovascular-critical-care
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