Mapping and tracing Grem1+ stromal cells in an ApcMin/+ mouse utilizing cryopreserved intestinal sections prepared via modified Swiss-roll technique

Mapping and tracing Grem1+ stromal cells in an ApcMin/+ mouse utilizing cryopreserved intestinal sections prepared via modified Swiss-roll technique

Summary: Grem1+ cancer-associated fibroblasts (CAFs) are crucial in colorectal cancer (CRC) development, yet technical challenges have limited understanding of their origins, spatiotemporal distribution, and potential roles. Here, we devised a custom mold, optimizing the gut Swiss-roll technique to...

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Bibliographic Details
Main Authors: Youheng Jiang, Zhang Fu, Yanfang Chen, Qunlong Jin, Yanming Yang, Zerong Lin, Changxue Li, Yunfei Gao, Zepeng Dong, Yang He, Xinjun Mao, Yulong He, Qingyuan Zhang, Qi Zhang, Ningning Li
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:iScience
Subjects:
Molecular biology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224023988
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