Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights

Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor, characterized by its aggressive behavior, limited treatment options, and poor prognosis. Despite advances in surgery, radiotherapy, and chemotherapy, the median survival of GBM patients remains disappointingly short. Recen...

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Bibliographic Details
Main Authors: Li Zhang, Yang Yang, Yanchu Li, Chenyu Wang, Chenbin Bian, Hongbin Wang, Feng Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Biomarker Research
Subjects:
Glioblastoma
Histone modifications
Histone acetylation
Histone methylation
Glioblastoma chemoresistance
Online Access:https://doi.org/10.1186/s40364-025-00788-w
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https://doi.org/10.1186/s40364-025-00788-w

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