Purinergic Receptor (P2X7R): A Promising Anti-Parkinson’s Drug Target

Purinergic Receptor (P2X7R): A Promising Anti-Parkinson’s Drug Target

Purpose: Parkinson’s disease (PD) is the fourth most common neurodegenerative disorder, characterized by degeneration of basal ganglia and a decrease in dopamine levels in the brain. Purinergic 2X7 receptors (P2X7Rs) serve as inflammation gatekeepers. They are found in both central and peripheral ne...

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Bibliographic Details
Main Authors: Saivarshini Magham, M. Lalith Kumar, Praveen Thaggikuppe Krishnamurthy, Neenu Shaji, Aishwarya Reddy Ramakkamma
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
pd
p2x7r
atp
microglia
cns
allosteric antagonists
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-14-807.pdf
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https://apb.tbzmed.ac.ir/PDF/apb-14-807.pdf

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