Ursolic acid inhibiting excessive reticulophagic flux contributes to alleviate ochratoxin A-induced endoplasmic reticulum stress- and mitochondrial-mediated apoptosis

Ursolic acid inhibiting excessive reticulophagic flux contributes to alleviate ochratoxin A-induced endoplasmic reticulum stress- and mitochondrial-mediated apoptosis

Foods and animal feeds frequently become contaminated with the nephrotoxic ochratoxin A (OTA). Our prior research has indicated that ursolic acid (UA), which is widely present in fruits and medicinal plants, has the potential to alleviate nephrotoxicity triggered by OTA. Additionally, excessive indu...

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Bibliographic Details
Main Authors: Huiqiong Deng, Wenying Chen, Lingyun Han, Boyang Zhang, Xun Luo, Song Yao, Hongwei Wang, Yao Zhou, Shuangchao Liu, Xiao Li Shen
Format: Article
Language:English
Published: Tsinghua University Press 2025-04-01
Series:Food Science and Human Wellness
Subjects:
ochratoxin a
ursolic acid
endoplasmic reticulum (er) stress
er-phagy
er-phagic flux
apoptosis
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250181
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