miR-155: An Important Role in Inflammation Response
MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in biological processes such as cell development, cell differentiation, cell proliferation, and cell apoptosis. The miRNA-mediated gene...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2022/7437281 |
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| _version_ | 1832562215833567232 |
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| author | Jingyan Hu Songli Huang Xiaoli Liu Yuan Zhang Shengli Wei Xiuhua Hu |
| author_facet | Jingyan Hu Songli Huang Xiaoli Liu Yuan Zhang Shengli Wei Xiuhua Hu |
| author_sort | Jingyan Hu |
| collection | DOAJ |
| description | MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in biological processes such as cell development, cell differentiation, cell proliferation, and cell apoptosis. The miRNA-mediated gene silencing is an important part of the regulation of gene expression in many kinds of diseases. miR-155, one of the best-characterized miRNAs, has been found to be closely related to physiological and pathological processes. What is more, miR-155 can be used as a potential therapeutic target for inflammatory diseases. We analyze the articles about miR-155 for nearly five years, review the advanced study on the function of miR-155 in different inflammatory cells like T cells, B cells, DCs, and macrophages, and then summarize the biological functions of miR-155 in different inflammatory cells. The widespread involvement of miR-155 in human diseases has led to a novel therapeutic approach between Chinese and Western medicine. |
| format | Article |
| id | doaj-art-c53bf5dbee624dcf98a4d7e9e4a9fff1 |
| institution | Kabale University |
| issn | 2314-7156 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-c53bf5dbee624dcf98a4d7e9e4a9fff12025-02-03T01:23:15ZengWileyJournal of Immunology Research2314-71562022-01-01202210.1155/2022/7437281miR-155: An Important Role in Inflammation ResponseJingyan Hu0Songli Huang1Xiaoli Liu2Yuan Zhang3Shengli Wei4Xiuhua Hu5School of Life SciencesSchool of Life SciencesXi’an Children’s HospitalSchool of Chinese Materia MedicaSchool of Chinese Materia MedicaSchool of Life SciencesMicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in biological processes such as cell development, cell differentiation, cell proliferation, and cell apoptosis. The miRNA-mediated gene silencing is an important part of the regulation of gene expression in many kinds of diseases. miR-155, one of the best-characterized miRNAs, has been found to be closely related to physiological and pathological processes. What is more, miR-155 can be used as a potential therapeutic target for inflammatory diseases. We analyze the articles about miR-155 for nearly five years, review the advanced study on the function of miR-155 in different inflammatory cells like T cells, B cells, DCs, and macrophages, and then summarize the biological functions of miR-155 in different inflammatory cells. The widespread involvement of miR-155 in human diseases has led to a novel therapeutic approach between Chinese and Western medicine.http://dx.doi.org/10.1155/2022/7437281 |
| spellingShingle | Jingyan Hu Songli Huang Xiaoli Liu Yuan Zhang Shengli Wei Xiuhua Hu miR-155: An Important Role in Inflammation Response Journal of Immunology Research |
| title | miR-155: An Important Role in Inflammation Response |
| title_full | miR-155: An Important Role in Inflammation Response |
| title_fullStr | miR-155: An Important Role in Inflammation Response |
| title_full_unstemmed | miR-155: An Important Role in Inflammation Response |
| title_short | miR-155: An Important Role in Inflammation Response |
| title_sort | mir 155 an important role in inflammation response |
| url | http://dx.doi.org/10.1155/2022/7437281 |
| work_keys_str_mv | AT jingyanhu mir155animportantroleininflammationresponse AT songlihuang mir155animportantroleininflammationresponse AT xiaoliliu mir155animportantroleininflammationresponse AT yuanzhang mir155animportantroleininflammationresponse AT shengliwei mir155animportantroleininflammationresponse AT xiuhuahu mir155animportantroleininflammationresponse |