Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria

Infectious diseases caused by microorganisms have gained worldwide attention in recent years. According to data compiled by the World Health Organization, the number of deaths resulting from infectious diseases is on the rise. In light of these dangers, the study of antibacterial materials has becom...

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Main Authors: Shrajan Kotian, Sonali Gupta, Yashoda Malgar Puttaiahgowda, Sanmit Shetty
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advances in Polymer Technology
Online Access:http://dx.doi.org/10.1155/2024/9941516
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author Shrajan Kotian
Sonali Gupta
Yashoda Malgar Puttaiahgowda
Sanmit Shetty
author_facet Shrajan Kotian
Sonali Gupta
Yashoda Malgar Puttaiahgowda
Sanmit Shetty
author_sort Shrajan Kotian
collection DOAJ
description Infectious diseases caused by microorganisms have gained worldwide attention in recent years. According to data compiled by the World Health Organization, the number of deaths resulting from infectious diseases is on the rise. In light of these dangers, the study of antibacterial materials has become increasingly vital. In this research, an antibacterial polymer was developed using poly(vinyl chloride) (PVC) and 4,4-diamminodiphenylmethane (DDM). The produced polymer’s chemical structure and thermal properties were investigated using Fourier-transform infrared spectroscopy, nuclear magnetic resonance, and thermo-gravimetric analysis. The antibacterial activity of the resulting PVC-g-DDM polymer was effective in killing both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The antimicrobial efficacy was tested using a spread plate method, demonstrating its potential utility in a variety of applications like biomedical, coatings, water purification systems, and others. Antimicrobial resistance is increasing, especially among bacteria that have acquired resistance to multiple therapeutics. To fully optimize and explore the polymer’s potential and its usage, more research is needed.
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publishDate 2024-01-01
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series Advances in Polymer Technology
spelling doaj-art-c5358b46c406435692b2ec070f19f0ce2025-02-03T05:57:04ZengWileyAdvances in Polymer Technology1098-23292024-01-01202410.1155/2024/9941516Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative BacteriaShrajan Kotian0Sonali Gupta1Yashoda Malgar Puttaiahgowda2Sanmit Shetty3Department of Chemical EngineeringDepartment of ChemistryDepartment of ChemistryDepartment of Chemical EngineeringInfectious diseases caused by microorganisms have gained worldwide attention in recent years. According to data compiled by the World Health Organization, the number of deaths resulting from infectious diseases is on the rise. In light of these dangers, the study of antibacterial materials has become increasingly vital. In this research, an antibacterial polymer was developed using poly(vinyl chloride) (PVC) and 4,4-diamminodiphenylmethane (DDM). The produced polymer’s chemical structure and thermal properties were investigated using Fourier-transform infrared spectroscopy, nuclear magnetic resonance, and thermo-gravimetric analysis. The antibacterial activity of the resulting PVC-g-DDM polymer was effective in killing both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The antimicrobial efficacy was tested using a spread plate method, demonstrating its potential utility in a variety of applications like biomedical, coatings, water purification systems, and others. Antimicrobial resistance is increasing, especially among bacteria that have acquired resistance to multiple therapeutics. To fully optimize and explore the polymer’s potential and its usage, more research is needed.http://dx.doi.org/10.1155/2024/9941516
spellingShingle Shrajan Kotian
Sonali Gupta
Yashoda Malgar Puttaiahgowda
Sanmit Shetty
Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
Advances in Polymer Technology
title Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
title_full Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
title_fullStr Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
title_full_unstemmed Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
title_short Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
title_sort synthesis and antibacterial activity of grafted poly vinyl chloride polymer against gram positive and gram negative bacteria
url http://dx.doi.org/10.1155/2024/9941516
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AT yashodamalgarputtaiahgowda synthesisandantibacterialactivityofgraftedpolyvinylchloridepolymeragainstgrampositiveandgramnegativebacteria
AT sanmitshetty synthesisandantibacterialactivityofgraftedpolyvinylchloridepolymeragainstgrampositiveandgramnegativebacteria