Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria
Infectious diseases caused by microorganisms have gained worldwide attention in recent years. According to data compiled by the World Health Organization, the number of deaths resulting from infectious diseases is on the rise. In light of these dangers, the study of antibacterial materials has becom...
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Language: | English |
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Wiley
2024-01-01
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Series: | Advances in Polymer Technology |
Online Access: | http://dx.doi.org/10.1155/2024/9941516 |
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author | Shrajan Kotian Sonali Gupta Yashoda Malgar Puttaiahgowda Sanmit Shetty |
author_facet | Shrajan Kotian Sonali Gupta Yashoda Malgar Puttaiahgowda Sanmit Shetty |
author_sort | Shrajan Kotian |
collection | DOAJ |
description | Infectious diseases caused by microorganisms have gained worldwide attention in recent years. According to data compiled by the World Health Organization, the number of deaths resulting from infectious diseases is on the rise. In light of these dangers, the study of antibacterial materials has become increasingly vital. In this research, an antibacterial polymer was developed using poly(vinyl chloride) (PVC) and 4,4-diamminodiphenylmethane (DDM). The produced polymer’s chemical structure and thermal properties were investigated using Fourier-transform infrared spectroscopy, nuclear magnetic resonance, and thermo-gravimetric analysis. The antibacterial activity of the resulting PVC-g-DDM polymer was effective in killing both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The antimicrobial efficacy was tested using a spread plate method, demonstrating its potential utility in a variety of applications like biomedical, coatings, water purification systems, and others. Antimicrobial resistance is increasing, especially among bacteria that have acquired resistance to multiple therapeutics. To fully optimize and explore the polymer’s potential and its usage, more research is needed. |
format | Article |
id | doaj-art-c5358b46c406435692b2ec070f19f0ce |
institution | Kabale University |
issn | 1098-2329 |
language | English |
publishDate | 2024-01-01 |
publisher | Wiley |
record_format | Article |
series | Advances in Polymer Technology |
spelling | doaj-art-c5358b46c406435692b2ec070f19f0ce2025-02-03T05:57:04ZengWileyAdvances in Polymer Technology1098-23292024-01-01202410.1155/2024/9941516Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative BacteriaShrajan Kotian0Sonali Gupta1Yashoda Malgar Puttaiahgowda2Sanmit Shetty3Department of Chemical EngineeringDepartment of ChemistryDepartment of ChemistryDepartment of Chemical EngineeringInfectious diseases caused by microorganisms have gained worldwide attention in recent years. According to data compiled by the World Health Organization, the number of deaths resulting from infectious diseases is on the rise. In light of these dangers, the study of antibacterial materials has become increasingly vital. In this research, an antibacterial polymer was developed using poly(vinyl chloride) (PVC) and 4,4-diamminodiphenylmethane (DDM). The produced polymer’s chemical structure and thermal properties were investigated using Fourier-transform infrared spectroscopy, nuclear magnetic resonance, and thermo-gravimetric analysis. The antibacterial activity of the resulting PVC-g-DDM polymer was effective in killing both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The antimicrobial efficacy was tested using a spread plate method, demonstrating its potential utility in a variety of applications like biomedical, coatings, water purification systems, and others. Antimicrobial resistance is increasing, especially among bacteria that have acquired resistance to multiple therapeutics. To fully optimize and explore the polymer’s potential and its usage, more research is needed.http://dx.doi.org/10.1155/2024/9941516 |
spellingShingle | Shrajan Kotian Sonali Gupta Yashoda Malgar Puttaiahgowda Sanmit Shetty Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria Advances in Polymer Technology |
title | Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria |
title_full | Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria |
title_fullStr | Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria |
title_full_unstemmed | Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria |
title_short | Synthesis and Antibacterial Activity of Grafted Poly(Vinyl Chloride) Polymer against Gram-Positive and Gram-Negative Bacteria |
title_sort | synthesis and antibacterial activity of grafted poly vinyl chloride polymer against gram positive and gram negative bacteria |
url | http://dx.doi.org/10.1155/2024/9941516 |
work_keys_str_mv | AT shrajankotian synthesisandantibacterialactivityofgraftedpolyvinylchloridepolymeragainstgrampositiveandgramnegativebacteria AT sonaligupta synthesisandantibacterialactivityofgraftedpolyvinylchloridepolymeragainstgrampositiveandgramnegativebacteria AT yashodamalgarputtaiahgowda synthesisandantibacterialactivityofgraftedpolyvinylchloridepolymeragainstgrampositiveandgramnegativebacteria AT sanmitshetty synthesisandantibacterialactivityofgraftedpolyvinylchloridepolymeragainstgrampositiveandgramnegativebacteria |