Differential Expression of Tyrosine Hydroxylase Protein and Apoptosis-Related Genes in Differentiated and Undifferentiated SH-SY5Y Neuroblastoma Cells Treated with MPP+
The human neuroblastoma SH-SY5Y cell line has been used as a dopaminergic cell model for Parkinson’s disease research. Whether undifferentiated or differentiated SH-SY5Y cells are more suitable remains controversial. This study aims to evaluate the expression of apoptosis-related mRNAs activated by...
Saved in:
| Main Authors: | Kawinthra Khwanraj, Chareerut Phruksaniyom, Suriyat Madlah, Permphan Dharmasaroja |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2015/734703 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evaluation of the Combination of Metformin and Rapamycin in an MPP+-Treated SH-SY5Y Model of Parkinson’s Disease
by: Chureerat Norradee, et al.
Published: (2023-01-01) -
Neuroprotective Effects of Alpha-Mangostin on MPP+-Induced Apoptotic Cell Death in Neuroblastoma SH-SY5Y Cells
by: Prachya Janhom, et al.
Published: (2015-01-01) -
eEF1A2 siRNA Suppresses MPP+-Induced Activation of Akt and mTOR and Potentiates Caspase-3 Activation in a Parkinson’s Disease Model
by: Kawinthra Khwanraj, et al.
Published: (2023-01-01) -
Alpha-Mangostin Alleviates Mitochondrial Damage and Autophagy Dysregulation in the MPP+ Cellular Model of Parkinson’s Disease
by: Korede Jacob Abraham, et al.
Published: (2025-01-01) -
Protective Role of Whey Protein Isolate on MPP<sup>+</sup>-Induced Differentiation of SH-SY5Y Cells by Modulating the Nrf2 Antioxidant Pathway
by: Panlekha Rungruang, et al.
Published: (2025-05-01)