Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements

This paper presents a method to improve confidence-interval (CI) estimation using individual uncertainty measures and weighted feature decisions for cuff-less blood-pressure (BP) measurement. We obtained uncertainty using Gaussian process regression (GPR). The CI obtained from the GPR model is compu...

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Main Authors: Soojeong Lee, Mugahed A. Al-antari, Gyanendra Prasad Joshi
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/12/2/131
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author Soojeong Lee
Mugahed A. Al-antari
Gyanendra Prasad Joshi
author_facet Soojeong Lee
Mugahed A. Al-antari
Gyanendra Prasad Joshi
author_sort Soojeong Lee
collection DOAJ
description This paper presents a method to improve confidence-interval (CI) estimation using individual uncertainty measures and weighted feature decisions for cuff-less blood-pressure (BP) measurement. We obtained uncertainty using Gaussian process regression (GPR). The CI obtained from the GPR model is computed using the distribution of BP estimates, which provides relatively wide CIs. Thus, we proposed a method to obtain improved CIs for individual subjects by applying bootstrap and uncertainty methods using the cuff-less BP estimates of each subject obtained through GPR. This study also introduced a novel method to estimate cuff-less BP with high fidelity by determining highly weighted features using weighted feature decisions. The standard deviation of the proposed method’s mean error is 2.94 mmHg and 1.50 mmHg for systolic blood pressure (SBP) and (DBP), respectively. The mean absolute error results were obtained by weighted feature determination combining GPR and gradient boosting algorithms (GBA) for SBP (1.46 mmHg) and DBP (0.69 mmHg). The study confirmed that the BP estimates were within the CI based on the test samples of almost all subjects. The weighted feature decisions combining GPR and GBA were more accurate and reliable for cuff-less BP estimation.
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spelling doaj-art-c4ebc6d972d34e1085e2bb5a4985a0a62025-08-20T03:11:58ZengMDPI AGBioengineering2306-53542025-01-0112213110.3390/bioengineering12020131Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure MeasurementsSoojeong Lee0Mugahed A. Al-antari1Gyanendra Prasad Joshi2Department of Computer Engineering, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul 05006, Republic of KoreaDepartment of Artificial Intelligence and Data Science, Sejong University, Seoul 05006, Republic of KoreaDepartment of AI Software, Kangwon National University, Kangwon State, Samcheok 10587, Republic of KoreaThis paper presents a method to improve confidence-interval (CI) estimation using individual uncertainty measures and weighted feature decisions for cuff-less blood-pressure (BP) measurement. We obtained uncertainty using Gaussian process regression (GPR). The CI obtained from the GPR model is computed using the distribution of BP estimates, which provides relatively wide CIs. Thus, we proposed a method to obtain improved CIs for individual subjects by applying bootstrap and uncertainty methods using the cuff-less BP estimates of each subject obtained through GPR. This study also introduced a novel method to estimate cuff-less BP with high fidelity by determining highly weighted features using weighted feature decisions. The standard deviation of the proposed method’s mean error is 2.94 mmHg and 1.50 mmHg for systolic blood pressure (SBP) and (DBP), respectively. The mean absolute error results were obtained by weighted feature determination combining GPR and gradient boosting algorithms (GBA) for SBP (1.46 mmHg) and DBP (0.69 mmHg). The study confirmed that the BP estimates were within the CI based on the test samples of almost all subjects. The weighted feature decisions combining GPR and GBA were more accurate and reliable for cuff-less BP estimation.https://www.mdpi.com/2306-5354/12/2/131uncertaintyconfidence intervalscuff-less blood-pressure estimationGaussian processes regressiongradient boosting algorithm
spellingShingle Soojeong Lee
Mugahed A. Al-antari
Gyanendra Prasad Joshi
Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements
Bioengineering
uncertainty
confidence intervals
cuff-less blood-pressure estimation
Gaussian processes regression
gradient boosting algorithm
title Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements
title_full Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements
title_fullStr Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements
title_full_unstemmed Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements
title_short Improved Confidence-Interval Estimations Using Uncertainty Measure and Weighted Feature Decisions for Cuff-Less Blood-Pressure Measurements
title_sort improved confidence interval estimations using uncertainty measure and weighted feature decisions for cuff less blood pressure measurements
topic uncertainty
confidence intervals
cuff-less blood-pressure estimation
Gaussian processes regression
gradient boosting algorithm
url https://www.mdpi.com/2306-5354/12/2/131
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AT mugahedaalantari improvedconfidenceintervalestimationsusinguncertaintymeasureandweightedfeaturedecisionsforcufflessbloodpressuremeasurements
AT gyanendraprasadjoshi improvedconfidenceintervalestimationsusinguncertaintymeasureandweightedfeaturedecisionsforcufflessbloodpressuremeasurements