What is the Helicobacter pylori Global Reinfection Rate?

Reinfection with any organism is related to the force of infection in the population and on both innate and acquired immunity to infection. Little is yet known about primary immune protection against Helicobacter pylori. Some data suggest that children can be recurrently infected, spontaneously elim...

Full description

Saved in:
Bibliographic Details
Main Author: Julie Parsonnet
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2003/567816
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832565530189365248
author Julie Parsonnet
author_facet Julie Parsonnet
author_sort Julie Parsonnet
collection DOAJ
description Reinfection with any organism is related to the force of infection in the population and on both innate and acquired immunity to infection. Little is yet known about primary immune protection against Helicobacter pylori. Some data suggest that children can be recurrently infected, spontaneously eliminating the organism only to be infected again and again until the organism takes hold. This pattern of recurrent infection is not observed in patients who receive eradication therapy for chronic infection. After eradication of infection, the rate of reinfection is probably slightly lower than the primary infection rate in that age group, suggesting some level of acquired immunity. In developed countries, reinfection of adults in unusual, and recurrence usually repesents failure of primary eradicaton rather than new infection. Some cases of reinfection do occur, however. Given that acquired immunity probably varies little from population to population, reinfections will most likely occur in areas where the force of infecton is high, ie, where both the prevalence of infection and the opportunities for transmission are high.
format Article
id doaj-art-c4bb485a327b47068c50902ae6719306
institution Kabale University
issn 0835-7900
language English
publishDate 2003-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-c4bb485a327b47068c50902ae67193062025-02-03T01:07:26ZengWileyCanadian Journal of Gastroenterology0835-79002003-01-0117Suppl B46B48B10.1155/2003/567816What is the Helicobacter pylori Global Reinfection Rate?Julie Parsonnet0Stanford University School of Medicine, Stanford, California, USAReinfection with any organism is related to the force of infection in the population and on both innate and acquired immunity to infection. Little is yet known about primary immune protection against Helicobacter pylori. Some data suggest that children can be recurrently infected, spontaneously eliminating the organism only to be infected again and again until the organism takes hold. This pattern of recurrent infection is not observed in patients who receive eradication therapy for chronic infection. After eradication of infection, the rate of reinfection is probably slightly lower than the primary infection rate in that age group, suggesting some level of acquired immunity. In developed countries, reinfection of adults in unusual, and recurrence usually repesents failure of primary eradicaton rather than new infection. Some cases of reinfection do occur, however. Given that acquired immunity probably varies little from population to population, reinfections will most likely occur in areas where the force of infecton is high, ie, where both the prevalence of infection and the opportunities for transmission are high.http://dx.doi.org/10.1155/2003/567816
spellingShingle Julie Parsonnet
What is the Helicobacter pylori Global Reinfection Rate?
Canadian Journal of Gastroenterology
title What is the Helicobacter pylori Global Reinfection Rate?
title_full What is the Helicobacter pylori Global Reinfection Rate?
title_fullStr What is the Helicobacter pylori Global Reinfection Rate?
title_full_unstemmed What is the Helicobacter pylori Global Reinfection Rate?
title_short What is the Helicobacter pylori Global Reinfection Rate?
title_sort what is the helicobacter pylori global reinfection rate
url http://dx.doi.org/10.1155/2003/567816
work_keys_str_mv AT julieparsonnet whatisthehelicobacterpyloriglobalreinfectionrate