The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women
Background. The impact of hypertension duration and the time of onset on the expression of metabolic syndrome (MS) and other CV risk factors, in perimenopausal women, have not been studied so far. Methods. A total of 202 women, old 47–59 years, and diagnosed with hypertension, were recruited from pr...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2019/9848125 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552388250042368 |
|---|---|
| author | Ljiljana Trtica Majnarić Ivo Martinović Šefket Šabanović Stjepan Rudan František Babič Thomas Wittlinger |
| author_facet | Ljiljana Trtica Majnarić Ivo Martinović Šefket Šabanović Stjepan Rudan František Babič Thomas Wittlinger |
| author_sort | Ljiljana Trtica Majnarić |
| collection | DOAJ |
| description | Background. The impact of hypertension duration and the time of onset on the expression of metabolic syndrome (MS) and other CV risk factors, in perimenopausal women, have not been studied so far. Methods. A total of 202 women, old 47–59 years, and diagnosed with hypertension, were recruited from primary care practices in eastern Croatia. The categories of hypertension duration were defined as <5, 5–10, and >10 years. Data were analyzed by standard statistical procedures. Results. The proportion of women with MS increases in parallel with hypertension duration (p = 0.025). Among the examined CV risk factors, significant increase in parallel with hypertension duration was found for body mass index (p = 0.007) and triglycerides (p = 0.07). The highest proportion of women with diabetes duration of less than 5 years, indicating recent diabetes onset, was found in the category of hypertension duration of less than 5 years, corresponding with the onset of hypertension in the time around menopause (p = 0.003). The strongest linear correlations with BMI and waist circumference were found for total serum cholesterol (r = 0.355 and 0.499, respectively). Conclusion. Hypertension onset at the time around menopause appears together with abdominal obesity and may be a driving force for CV risk factor accumulation in postmenopausal women. |
| format | Article |
| id | doaj-art-c4a9823720464ec1b834ccdea8eee21a |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-c4a9823720464ec1b834ccdea8eee21a2025-02-03T05:58:55ZengWileyInternational Journal of Hypertension2090-03842090-03922019-01-01201910.1155/2019/98481259848125The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal WomenLjiljana Trtica Majnarić0Ivo Martinović1Šefket Šabanović2Stjepan Rudan3František Babič4Thomas Wittlinger5Faculty of Medicine, University Josip Juraj Strossmayer, Department of Internal Medicine, Family Medicine and the History of Medicine, Osijek, CroatiaFaculty of Dental Medicine and Health, University Josip Juraj Strossmayer, Department of Public Health, Osijek, CroatiaFaculty of Medicine, University Josip Juraj Strossmayer, Department of Internal Medicine, Family Medicine and the History of Medicine, Osijek, CroatiaFaculty of Dental Medicine and Health, University Josip Juraj Strossmayer, Department of Public Health, Osijek, CroatiaDepartment of Cybernetics and Artificial Intelligence, Faculty of Electrical Engineering and Informatics, Technical University of Košice, Letná 9, Košice 04200, SlovakiaAsklepios Harzkliniken, Department of Cardiology, Köslinerstr 12, Goslar 38642, GermanyBackground. The impact of hypertension duration and the time of onset on the expression of metabolic syndrome (MS) and other CV risk factors, in perimenopausal women, have not been studied so far. Methods. A total of 202 women, old 47–59 years, and diagnosed with hypertension, were recruited from primary care practices in eastern Croatia. The categories of hypertension duration were defined as <5, 5–10, and >10 years. Data were analyzed by standard statistical procedures. Results. The proportion of women with MS increases in parallel with hypertension duration (p = 0.025). Among the examined CV risk factors, significant increase in parallel with hypertension duration was found for body mass index (p = 0.007) and triglycerides (p = 0.07). The highest proportion of women with diabetes duration of less than 5 years, indicating recent diabetes onset, was found in the category of hypertension duration of less than 5 years, corresponding with the onset of hypertension in the time around menopause (p = 0.003). The strongest linear correlations with BMI and waist circumference were found for total serum cholesterol (r = 0.355 and 0.499, respectively). Conclusion. Hypertension onset at the time around menopause appears together with abdominal obesity and may be a driving force for CV risk factor accumulation in postmenopausal women.http://dx.doi.org/10.1155/2019/9848125 |
| spellingShingle | Ljiljana Trtica Majnarić Ivo Martinović Šefket Šabanović Stjepan Rudan František Babič Thomas Wittlinger The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women International Journal of Hypertension |
| title | The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women |
| title_full | The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women |
| title_fullStr | The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women |
| title_full_unstemmed | The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women |
| title_short | The Effect of Hypertension Duration and the Age of Onset on CV Risk Factors Expression in Perimenopausal Women |
| title_sort | effect of hypertension duration and the age of onset on cv risk factors expression in perimenopausal women |
| url | http://dx.doi.org/10.1155/2019/9848125 |
| work_keys_str_mv | AT ljiljanatrticamajnaric theeffectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT ivomartinovic theeffectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT sefketsabanovic theeffectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT stjepanrudan theeffectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT frantisekbabic theeffectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT thomaswittlinger theeffectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT ljiljanatrticamajnaric effectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT ivomartinovic effectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT sefketsabanovic effectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT stjepanrudan effectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT frantisekbabic effectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen AT thomaswittlinger effectofhypertensiondurationandtheageofonsetoncvriskfactorsexpressioninperimenopausalwomen |