A Subunit Vaccine Harboring the Fusion Capsid Proteins of Porcine Circovirus Types 2, 3, and 4 Induces Protective Immune Responses in a Mouse Model

A Subunit Vaccine Harboring the Fusion Capsid Proteins of Porcine Circovirus Types 2, 3, and 4 Induces Protective Immune Responses in a Mouse Model

Coinfections with porcine circovirus types 2, 3, and 4 (PCV2, PCV3, and PCV4) are increasingly being detected in the swine industry. However, there is no commercially available vaccine which prevents coinfection with PCV2, PCV3, and PCV4. The development of a vaccine expressing capsid (Cap) fusion p...

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Bibliographic Details
Main Authors: Qikai Wang, Ran Zhang, Yue Wang, Ying Wang, Libin Liang, Haili Ma, Haidong Wang, Longlong Si, Xingchen Wu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Viruses
Subjects:
porcine circovirus
capsid
antigenic epitope
fusion protein
subunit vaccine
immunogenicity
Online Access:https://www.mdpi.com/1999-4915/16/12/1964
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