Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one
By the action of 2-amino-5-methylthio-1,3,4-thiadiazole, 3-amino-5-methylisoxazole, 2-amino-6-fluorobenzothiazole, 2-amino-5-chloropyridine, respectively, on 4-chloro-2-oxo-2H-chromene-3-sulfonyl chloride, the corresponding 9-methylthio-7,7-dioxo-7,7a-dihydro-5-oxo-7λ6,10-dithia-8,11-diaza-cyclopent...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2011/402975 |
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| author | Majlinda Daci-Ajvazi Sevdije Govori Shuhreta Omeragiq |
| author_facet | Majlinda Daci-Ajvazi Sevdije Govori Shuhreta Omeragiq |
| author_sort | Majlinda Daci-Ajvazi |
| collection | DOAJ |
| description | By the action of 2-amino-5-methylthio-1,3,4-thiadiazole, 3-amino-5-methylisoxazole, 2-amino-6-fluorobenzothiazole, 2-amino-5-chloropyridine, respectively, on 4-chloro-2-oxo-2H-chromene-3-sulfonyl chloride, the corresponding 9-methylthio-7,7-dioxo-7,7a-dihydro-5-oxo-7λ6,10-dithia-8,11-diaza-cyclopenta[b] phenantren-6-one, 9-methyl-7,7-dioxo-7H-5,8-dioxa-7λ6-thia-7a,11-diaza-cyclopenta[b] phenantren-6-one, 9-fluoro-7,7-dioxo-7H-5-oxa-7λ6,12-dithia-7a,13-diaza-indeno[1,2-b] phenantren-6-one and 9-Chloro-7,7-dioxo-7H-5-oxa-7λ6-thia-7a,12-diaza-benzo[α]anthracen -6-one were formed and they have been isolated in satisfying yields. Based on the biological activity of chromene-2-ones and heterocyclic compounds condensed in position 3 and 4, we also studied microbiological activity of these new compounds (5-8), against Staphylococcus aureus ATCC 25923, Streptococcus pneumoniae, Aeromonas Salmonicida, Bacillus spp and some of them exhibited significant activity. |
| format | Article |
| id | doaj-art-c49b6b56824a45de8e2448a4134659c3 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-c49b6b56824a45de8e2448a4134659c32025-02-03T01:13:00ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-01841522152710.1155/2011/402975Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-oneMajlinda Daci-Ajvazi0Sevdije Govori1Shuhreta Omeragiq2University of Prishtina, Faculty of Natural and Mathematical Sciences, Department of Chemistry, 10000 Prishtina, KosovoUniversity of Prishtina, Faculty of Natural and Mathematical Sciences, Department of Chemistry, 10000 Prishtina, KosovoMicrobiological Laboratory of Regional Water Company, KosovoBy the action of 2-amino-5-methylthio-1,3,4-thiadiazole, 3-amino-5-methylisoxazole, 2-amino-6-fluorobenzothiazole, 2-amino-5-chloropyridine, respectively, on 4-chloro-2-oxo-2H-chromene-3-sulfonyl chloride, the corresponding 9-methylthio-7,7-dioxo-7,7a-dihydro-5-oxo-7λ6,10-dithia-8,11-diaza-cyclopenta[b] phenantren-6-one, 9-methyl-7,7-dioxo-7H-5,8-dioxa-7λ6-thia-7a,11-diaza-cyclopenta[b] phenantren-6-one, 9-fluoro-7,7-dioxo-7H-5-oxa-7λ6,12-dithia-7a,13-diaza-indeno[1,2-b] phenantren-6-one and 9-Chloro-7,7-dioxo-7H-5-oxa-7λ6-thia-7a,12-diaza-benzo[α]anthracen -6-one were formed and they have been isolated in satisfying yields. Based on the biological activity of chromene-2-ones and heterocyclic compounds condensed in position 3 and 4, we also studied microbiological activity of these new compounds (5-8), against Staphylococcus aureus ATCC 25923, Streptococcus pneumoniae, Aeromonas Salmonicida, Bacillus spp and some of them exhibited significant activity.http://dx.doi.org/10.1155/2011/402975 |
| spellingShingle | Majlinda Daci-Ajvazi Sevdije Govori Shuhreta Omeragiq Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one E-Journal of Chemistry |
| title | Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one |
| title_full | Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one |
| title_fullStr | Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one |
| title_full_unstemmed | Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one |
| title_short | Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one |
| title_sort | synthesis and microbiological activity of some newly synthesized derivatives of 2 oxo 2h chromen 2 one |
| url | http://dx.doi.org/10.1155/2011/402975 |
| work_keys_str_mv | AT majlindadaciajvazi synthesisandmicrobiologicalactivityofsomenewlysynthesizedderivativesof2oxo2hchromen2one AT sevdijegovori synthesisandmicrobiologicalactivityofsomenewlysynthesizedderivativesof2oxo2hchromen2one AT shuhretaomeragiq synthesisandmicrobiologicalactivityofsomenewlysynthesizedderivativesof2oxo2hchromen2one |