PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways

PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways

The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis is upregulated by PPAR. Several pharmacological compounds (acting as antioxidants and, hence, atheroprotective) stimulate both...

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Bibliographic Details
Main Authors:	Jordi Camps, Anabel García-Heredia, Anna Rull, Carlos Alonso-Villaverde, Gerard Aragonès, Raúl Beltrán-Debón, Esther Rodríguez-Gallego, Jorge Joven
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	PPAR Research
Online Access:	http://dx.doi.org/10.1155/2012/616371
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