Variations to the Nanotube Surface for Bone Regeneration
The complex mechanisms of the bone cell-surface interactions are yet to be completely understood, and researchers continue to strive to uncover the fully optimized implant material for perfect osseointegration. A particularly fascinating area of research involves the study of nanostructured surfaces...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2013/513680 |
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| _version_ | 1832553223486963712 |
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| author | Christine J. Frandsen Karla S. Brammer Sungho Jin |
| author_facet | Christine J. Frandsen Karla S. Brammer Sungho Jin |
| author_sort | Christine J. Frandsen |
| collection | DOAJ |
| description | The complex mechanisms of the bone cell-surface interactions are yet to be completely understood, and researchers continue to strive to uncover the fully optimized implant material for perfect osseointegration. A particularly fascinating area of research involves the study of nanostructured surfaces, which are believed to enhance osteogenic behavior, possibly due to the mimicry of components of the extracellular matrix of bone. There is a growing body of data that emphasizes the promise of the titanium oxide (TiO2) nanotube architecture as an advanced orthopedic implant material. The review herein highlights findings regarding TiO2 nanotube surfaces for bone regeneration and the osteogenic effects of minute changes to the surface such as tube size and surface chemistry. |
| format | Article |
| id | doaj-art-c4892a9c10bb4834b0a2db7cff4d3a78 |
| institution | Kabale University |
| issn | 1687-8787 1687-8795 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomaterials |
| spelling | doaj-art-c4892a9c10bb4834b0a2db7cff4d3a782025-02-03T05:55:18ZengWileyInternational Journal of Biomaterials1687-87871687-87952013-01-01201310.1155/2013/513680513680Variations to the Nanotube Surface for Bone RegenerationChristine J. Frandsen0Karla S. Brammer1Sungho Jin2Materials Science and Engineering Program, University of California, San Diego, La Jolla, CA 92093-0411, USAMaterials Science and Engineering Program, University of California, San Diego, La Jolla, CA 92093-0411, USAMaterials Science and Engineering Program, University of California, San Diego, La Jolla, CA 92093-0411, USAThe complex mechanisms of the bone cell-surface interactions are yet to be completely understood, and researchers continue to strive to uncover the fully optimized implant material for perfect osseointegration. A particularly fascinating area of research involves the study of nanostructured surfaces, which are believed to enhance osteogenic behavior, possibly due to the mimicry of components of the extracellular matrix of bone. There is a growing body of data that emphasizes the promise of the titanium oxide (TiO2) nanotube architecture as an advanced orthopedic implant material. The review herein highlights findings regarding TiO2 nanotube surfaces for bone regeneration and the osteogenic effects of minute changes to the surface such as tube size and surface chemistry.http://dx.doi.org/10.1155/2013/513680 |
| spellingShingle | Christine J. Frandsen Karla S. Brammer Sungho Jin Variations to the Nanotube Surface for Bone Regeneration International Journal of Biomaterials |
| title | Variations to the Nanotube Surface for Bone Regeneration |
| title_full | Variations to the Nanotube Surface for Bone Regeneration |
| title_fullStr | Variations to the Nanotube Surface for Bone Regeneration |
| title_full_unstemmed | Variations to the Nanotube Surface for Bone Regeneration |
| title_short | Variations to the Nanotube Surface for Bone Regeneration |
| title_sort | variations to the nanotube surface for bone regeneration |
| url | http://dx.doi.org/10.1155/2013/513680 |
| work_keys_str_mv | AT christinejfrandsen variationstothenanotubesurfaceforboneregeneration AT karlasbrammer variationstothenanotubesurfaceforboneregeneration AT sunghojin variationstothenanotubesurfaceforboneregeneration |