Polycyclic aromatic hydrocarbons promote tumorigenesis of gallbladder cancer via aryl hydrocarbon Receptor-HEGBC positive feedback axis

Polycyclic aromatic hydrocarbons promote tumorigenesis of gallbladder cancer via aryl hydrocarbon Receptor-HEGBC positive feedback axis

Summary: Gallbladder cancer (GBC) is a highly aggressive tumor associated with risk factors, such as chronic infection, gallstones, and exposure to harmful chemicals. Our study explores the role of polycyclic aromatic hydrocarbons (PAHs) and long noncoding RNA HEGBC in GBC progression. We found that...

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Bibliographic Details
Main Authors: Lei Yuan, Yumeng Zhang, Jianguo Xu, Feng Liu, Yingchao Liang, Beili Wang, Meihong Wu, Zhiyuan Fan, Liang Yang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
biological sciences
cancer systems biology
health sciences
internal medicine
medical specialty
medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007667
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