Feline Papillomatosis
Different types of feline papillomaviruses (PVs) are associated with a variety of skin lesions and neoplasia, such as papillomas and cell carcinomas, but the virus can also be found in healthy skin. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent boar...
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2025-01-01
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| author | Herman Egberink Katrin Hartmann Ralf Mueller Maria Grazia Pennisi Sándor Belák Séverine Tasker Karin Möstl Diane D. Addie Corine Boucraut-Baralon Tadeusz Frymus Regina Hofmann-Lehmann Fulvio Marsilio Etienne Thiry Uwe Truyen Margaret J. Hosie |
| author_facet | Herman Egberink Katrin Hartmann Ralf Mueller Maria Grazia Pennisi Sándor Belák Séverine Tasker Karin Möstl Diane D. Addie Corine Boucraut-Baralon Tadeusz Frymus Regina Hofmann-Lehmann Fulvio Marsilio Etienne Thiry Uwe Truyen Margaret J. Hosie |
| author_sort | Herman Egberink |
| collection | DOAJ |
| description | Different types of feline papillomaviruses (PVs) are associated with a variety of skin lesions and neoplasia, such as papillomas and cell carcinomas, but the virus can also be found in healthy skin. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of veterinary experts on feline infectious diseases from 11 European Countries, discusses the current knowledge of feline PV infections. Cats most likely become infected through lesions or abrasions of the skin. Most PV infections remain asymptomatic. Besides cat-specific PVs, DNA sequences most closely related to human and bovine PVs have been detected in feline skin lesions. Diagnosis is supported by the histological detection of PV-induced cell changes and intralesional detection of viral antigen (immunostaining) or viral DNA (in situ hybridization). Immunostaining of p16CDKN2A protein (p16) can be performed as a proxy marker for PV-induced neoplasms. There is no specific treatment for PV-induced skin lesions. Spontaneous regression commonly occurs. In the case of invasive squamous cell carcinoma (ISCC), complete excision should be considered, if possible. |
| format | Article |
| id | doaj-art-c464812398f8416f8a293ab719c3d863 |
| institution | Kabale University |
| issn | 1999-4915 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj-art-c464812398f8416f8a293ab719c3d8632025-01-24T13:52:26ZengMDPI AGViruses1999-49152025-01-011715910.3390/v17010059Feline PapillomatosisHerman Egberink0Katrin Hartmann1Ralf Mueller2Maria Grazia Pennisi3Sándor Belák4Séverine Tasker5Karin Möstl6Diane D. Addie7Corine Boucraut-Baralon8Tadeusz Frymus9Regina Hofmann-Lehmann10Fulvio Marsilio11Etienne Thiry12Uwe Truyen13Margaret J. Hosie14Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, University of Utrecht, 3584 CL Utrecht, The NetherlandsClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, GermanyClinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, GermanyI Periodeuti ASC, 89122 Reggio Calabria, ItalyDepartment of Biomedical Sciences and Veterinary Public Health (BVF), Swedish University of Agri-Cultural Sciences (SLU), P.O. Box 7036, 750 07 Uppsala, SwedenBristol Veterinary School, University of Bristol, Bristol BS40 5DU, UKRetired from Institute of Virology, Department for Pathobiology, University of Veterinary Medicine, 1210 Vienna, AustriaIndependent Researcher, 64000 Pyrénées Aquitaine, FranceScanelis Laboratory, 31770 Colomiers, FranceDepartment of Small Animal Diseases with Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences—SGGW, 02-787 Warsaw, PolandClinical Laboratory, Department of Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandFaculty of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, ItalyVeterinary Virology and Animal Viral Diseases, Department of Infectious and Parasitic Diseases, FARAH Research Centre, Faculty of Veterinary Medicine, Liège University, B-4000 Liège, BelgiumInstitute of Animal Hygiene and Veterinary Public Health, University of Leipzig, 04103 Leipzig, GermanyMRC—University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UKDifferent types of feline papillomaviruses (PVs) are associated with a variety of skin lesions and neoplasia, such as papillomas and cell carcinomas, but the virus can also be found in healthy skin. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of veterinary experts on feline infectious diseases from 11 European Countries, discusses the current knowledge of feline PV infections. Cats most likely become infected through lesions or abrasions of the skin. Most PV infections remain asymptomatic. Besides cat-specific PVs, DNA sequences most closely related to human and bovine PVs have been detected in feline skin lesions. Diagnosis is supported by the histological detection of PV-induced cell changes and intralesional detection of viral antigen (immunostaining) or viral DNA (in situ hybridization). Immunostaining of p16CDKN2A protein (p16) can be performed as a proxy marker for PV-induced neoplasms. There is no specific treatment for PV-induced skin lesions. Spontaneous regression commonly occurs. In the case of invasive squamous cell carcinoma (ISCC), complete excision should be considered, if possible.https://www.mdpi.com/1999-4915/17/1/59papillomavirusfelineFcaPVpapillomaskin neoplasm |
| spellingShingle | Herman Egberink Katrin Hartmann Ralf Mueller Maria Grazia Pennisi Sándor Belák Séverine Tasker Karin Möstl Diane D. Addie Corine Boucraut-Baralon Tadeusz Frymus Regina Hofmann-Lehmann Fulvio Marsilio Etienne Thiry Uwe Truyen Margaret J. Hosie Feline Papillomatosis Viruses papillomavirus feline FcaPV papilloma skin neoplasm |
| title | Feline Papillomatosis |
| title_full | Feline Papillomatosis |
| title_fullStr | Feline Papillomatosis |
| title_full_unstemmed | Feline Papillomatosis |
| title_short | Feline Papillomatosis |
| title_sort | feline papillomatosis |
| topic | papillomavirus feline FcaPV papilloma skin neoplasm |
| url | https://www.mdpi.com/1999-4915/17/1/59 |
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