Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess

Genital ulcer is one of the main clinical symptoms of Behçet disease; ulcers mostly occur in the vulva and are usually quite painful. We present an unusual case of Behçet disease wherein a painless genital ulcer was localized in the vagina. Our case is of a 43-year-old woman diagnosed with Behçet di...

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Main Authors: Soichiro Obata, Koji Kobayashi, Misaki Toda, Etsuko Miyagi, Shigeru Aoki
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2019/2953676
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author Soichiro Obata
Koji Kobayashi
Misaki Toda
Etsuko Miyagi
Shigeru Aoki
author_facet Soichiro Obata
Koji Kobayashi
Misaki Toda
Etsuko Miyagi
Shigeru Aoki
author_sort Soichiro Obata
collection DOAJ
description Genital ulcer is one of the main clinical symptoms of Behçet disease; ulcers mostly occur in the vulva and are usually quite painful. We present an unusual case of Behçet disease wherein a painless genital ulcer was localized in the vagina. Our case is of a 43-year-old woman diagnosed with Behçet disease that was controlled with prednisolone. She became pregnant and developed fever, oral ulcers, and arthralgia at 16 weeks of gestation. Although a relapse of Behçet disease was suspected, ulceration and pain of the vulva were not observed. At 18 and 28 weeks of gestation, a vaginal ulcer was observed during regular prenatal examination, but the patient had no pain or other symptoms in the vulva. The vaginal ulcer healed at 29 weeks of gestation. No recurrence of the vaginal ulcer and other symptoms of Behçet disease were seen on subsequent follow-up examination at 1 month after delivery. Although genital ulcers of Behçet disease are common in the vulva and are generally painful, if they are located in the vagina, they can be painless. If Behçet disease is suspected based on other symptoms, a vaginal examination should be conducted as necessary for accurate evaluation of Behçet disease.
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publishDate 2019-01-01
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series Case Reports in Rheumatology
spelling doaj-art-c45fffd3b618449488682711db1d85e82025-02-03T01:23:18ZengWileyCase Reports in Rheumatology2090-68892090-68972019-01-01201910.1155/2019/29536762953676Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to AssessSoichiro Obata0Koji Kobayashi1Misaki Toda2Etsuko Miyagi3Shigeru Aoki4Perinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, JapanCenter for Rheumatic Disease, Yokohama City University Medical Center, Yokohama, JapanPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, JapanDepartment of Obstetrics and Gynecology, Yokohama City University Hospital, Yokohama, JapanPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, JapanGenital ulcer is one of the main clinical symptoms of Behçet disease; ulcers mostly occur in the vulva and are usually quite painful. We present an unusual case of Behçet disease wherein a painless genital ulcer was localized in the vagina. Our case is of a 43-year-old woman diagnosed with Behçet disease that was controlled with prednisolone. She became pregnant and developed fever, oral ulcers, and arthralgia at 16 weeks of gestation. Although a relapse of Behçet disease was suspected, ulceration and pain of the vulva were not observed. At 18 and 28 weeks of gestation, a vaginal ulcer was observed during regular prenatal examination, but the patient had no pain or other symptoms in the vulva. The vaginal ulcer healed at 29 weeks of gestation. No recurrence of the vaginal ulcer and other symptoms of Behçet disease were seen on subsequent follow-up examination at 1 month after delivery. Although genital ulcers of Behçet disease are common in the vulva and are generally painful, if they are located in the vagina, they can be painless. If Behçet disease is suspected based on other symptoms, a vaginal examination should be conducted as necessary for accurate evaluation of Behçet disease.http://dx.doi.org/10.1155/2019/2953676
spellingShingle Soichiro Obata
Koji Kobayashi
Misaki Toda
Etsuko Miyagi
Shigeru Aoki
Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess
Case Reports in Rheumatology
title Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess
title_full Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess
title_fullStr Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess
title_full_unstemmed Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess
title_short Genital Ulcer of Behçet Disease Localized in the Vagina May Lack Pain, Making It Difficult to Assess
title_sort genital ulcer of behcet disease localized in the vagina may lack pain making it difficult to assess
url http://dx.doi.org/10.1155/2019/2953676
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