Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis

Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis

Elevated levels of IL-6 in plasma are associated with the severity of visceral leishmaniasis (VL). The clinical manifestations of VL vary among patients, influenced by host factors and the virulence of the Leishmania infantum parasite. Considering that severe VL may result from an exaggerated inflam...

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Main Authors: Amanda Miranda da Silva, Kátia Silene Sousa Carvalho, Caio Andrey Bezerra Januário, Raquel Gomes de Sena Carneiro Caldas, Bianka Lopes da Silva Paulino, Débora Cavalcante Braz, Dorcas Lamounier Costa, Gabriel da Luz Wallau, Wilson Jose da Silva Junior, Carlos Henrique Nery Costa
Format: Article
Language:English
Published: Cambridge University Press
Series:Parasitology
Subjects:
genome-wide association study
genomics
interleukin-6
Leishmania infantum
visceral leishmaniasis
Online Access:https://www.cambridge.org/core/product/identifier/S0031182024001598/type/journal_article
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