A Study to Inform the Design of a National Multicentre Randomised Controlled Trial to Evaluate If Reducing Serum Phosphate to Normal Levels Improves Clinical Outcomes including Mortality, Cardiovascular Events, Bone Pain, or Fracture in Patients on Dialysis
Background. Retrospective, observational studies link high phosphate with mortality in dialysis patients. This generates research hypotheses but does not establish “cause-and-effect.” A large randomised controlled trial (RCT) of about 3000 patients randomised 50 : 50 to lower or higher phosphate ran...
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Main Authors: | Ramya Bhargava, Philip A. Kalra, Paul Brenchley, Helen Hurst, Alastair Hutchison |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | International Journal of Nephrology |
Online Access: | http://dx.doi.org/10.1155/2015/579434 |
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