Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation
Purpose. To investigate the choroidal thickness (CT) and retinal thickness (RT) in highly myopic tessellated eyes. Methods. In this study, 115 highly myopic eyes were recruited and divided as tessellated fundus (n=93) and normal fundus (n=22). RT and CT were quantified using optical coherence tomogr...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2018/2181602 |
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| author | Yanping Zhou Minlu Song Minwen Zhou Yiming Liu Fenghua Wang Xiaodong Sun |
| author_facet | Yanping Zhou Minlu Song Minwen Zhou Yiming Liu Fenghua Wang Xiaodong Sun |
| author_sort | Yanping Zhou |
| collection | DOAJ |
| description | Purpose. To investigate the choroidal thickness (CT) and retinal thickness (RT) in highly myopic tessellated eyes. Methods. In this study, 115 highly myopic eyes were recruited and divided as tessellated fundus (n=93) and normal fundus (n=22). RT and CT were quantified using optical coherence tomography with enhanced depth imaging (EDI-OCT). Correlation between subfoveal CT (SFCT) and tessellation was analyzed using logistic regression models. Results. Tessellated fundus eyes had thinner CT than did normal fundus eyes, while RT was not statistically different across groups. The tessellated eyes had a thinner choroid than did the control eyes at all measured macular locations (all P<0.05). After adjustment for AL, age, and gender, the SFCT was significantly associated with tessellation. The odds ratio (OR) and 95% confidence interval (CI) was 0.975 (0.960–0.990, P=0.001, binary logistics regression) and 0.991 (0.984–0.999, P=0.022, Cox regression). The area under the curve (AUC) of SFCT was the greatest for detecting tessellation (AUC = 0.824, P<0.001). For sensitivity and specificity analyses, SFCT had the highest diagnostic value (sensitivity = 81.8%, specificity = 74.2%). Conclusions. Highly myopic eyes with tessellation have thinner CT than do normal highly myopic eyes. CT may serve as an early pathologic predictor of high myopia. |
| format | Article |
| id | doaj-art-c44bd134c6174130b87bcb7f7bd3aa79 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-c44bd134c6174130b87bcb7f7bd3aa792025-02-03T05:46:15ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/21816022181602Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: TessellationYanping Zhou0Minlu Song1Minwen Zhou2Yiming Liu3Fenghua Wang4Xiaodong Sun5Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaPurpose. To investigate the choroidal thickness (CT) and retinal thickness (RT) in highly myopic tessellated eyes. Methods. In this study, 115 highly myopic eyes were recruited and divided as tessellated fundus (n=93) and normal fundus (n=22). RT and CT were quantified using optical coherence tomography with enhanced depth imaging (EDI-OCT). Correlation between subfoveal CT (SFCT) and tessellation was analyzed using logistic regression models. Results. Tessellated fundus eyes had thinner CT than did normal fundus eyes, while RT was not statistically different across groups. The tessellated eyes had a thinner choroid than did the control eyes at all measured macular locations (all P<0.05). After adjustment for AL, age, and gender, the SFCT was significantly associated with tessellation. The odds ratio (OR) and 95% confidence interval (CI) was 0.975 (0.960–0.990, P=0.001, binary logistics regression) and 0.991 (0.984–0.999, P=0.022, Cox regression). The area under the curve (AUC) of SFCT was the greatest for detecting tessellation (AUC = 0.824, P<0.001). For sensitivity and specificity analyses, SFCT had the highest diagnostic value (sensitivity = 81.8%, specificity = 74.2%). Conclusions. Highly myopic eyes with tessellation have thinner CT than do normal highly myopic eyes. CT may serve as an early pathologic predictor of high myopia.http://dx.doi.org/10.1155/2018/2181602 |
| spellingShingle | Yanping Zhou Minlu Song Minwen Zhou Yiming Liu Fenghua Wang Xiaodong Sun Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation Journal of Ophthalmology |
| title | Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation |
| title_full | Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation |
| title_fullStr | Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation |
| title_full_unstemmed | Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation |
| title_short | Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation |
| title_sort | choroidal and retinal thickness of highly myopic eyes with early stage of myopic chorioretinopathy tessellation |
| url | http://dx.doi.org/10.1155/2018/2181602 |
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