Biopolymer-based bone scaffold for controlled Pt (IV) prodrug release and synergistic photothermal-chemotherapy and immunotherapy in osteosarcoma
Abstract Achieving bone defect repair while preventing tumor recurrence after osteosarcoma surgery has consistently posed a clinical challenge. Local treatment with 3D-printed scaffolds loaded with chemotherapeutic drugs can exert certain effects in tumor inhibition and bone regeneration. However, t...
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| Main Authors: | Zuyun Yan, Youwen Deng, Liping Huang, Jin Zeng, Dong Wang, Zhaochen Tong, Qizhi Fan, Wei Tan, Jinpeng Yan, Xiaofang Zang, Shijie Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
|
| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-025-03253-w |
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