Biopolymer-based bone scaffold for controlled Pt (IV) prodrug release and synergistic photothermal-chemotherapy and immunotherapy in osteosarcoma

Biopolymer-based bone scaffold for controlled Pt (IV) prodrug release and synergistic photothermal-chemotherapy and immunotherapy in osteosarcoma

Abstract Achieving bone defect repair while preventing tumor recurrence after osteosarcoma surgery has consistently posed a clinical challenge. Local treatment with 3D-printed scaffolds loaded with chemotherapeutic drugs can exert certain effects in tumor inhibition and bone regeneration. However, t...

Full description

Saved in:
Bibliographic Details
Main Authors: Zuyun Yan, Youwen Deng, Liping Huang, Jin Zeng, Dong Wang, Zhaochen Tong, Qizhi Fan, Wei Tan, Jinpeng Yan, Xiaofang Zang, Shijie Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Nanobiotechnology
Subjects:
Antitumour
Pt (IV) prodrugs
Photothermal therapy
Immunity
Bone regeneration
Online Access:https://doi.org/10.1186/s12951-025-03253-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12951-025-03253-w

Similar Items