To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis

Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyro...

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Main Authors: Tania Ahuja, Olivia Nuti, Cameron Kemal, Darren Kang, Eugene Yuriditsky, James M. Horowitz, Raymond A. Pashun
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2023/1563732
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author Tania Ahuja
Olivia Nuti
Cameron Kemal
Darren Kang
Eugene Yuriditsky
James M. Horowitz
Raymond A. Pashun
author_facet Tania Ahuja
Olivia Nuti
Cameron Kemal
Darren Kang
Eugene Yuriditsky
James M. Horowitz
Raymond A. Pashun
author_sort Tania Ahuja
collection DOAJ
description Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy.
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institution Kabale University
issn 2090-6412
language English
publishDate 2023-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-c41384990a1e496f9af1de9b46cbad5b2025-02-03T06:47:46ZengWileyCase Reports in Cardiology2090-64122023-01-01202310.1155/2023/1563732To PLEX or Not to PLEX for Amiodarone-Induced ThyrotoxicosisTania Ahuja0Olivia Nuti1Cameron Kemal2Darren Kang3Eugene Yuriditsky4James M. Horowitz5Raymond A. Pashun6Department of MedicineDepartment of PharmacyDepartment of MedicineDepartment of Advanced Practice PractitionersDepartment of MedicineDepartment of MedicineDepartment of MedicineAmiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy.http://dx.doi.org/10.1155/2023/1563732
spellingShingle Tania Ahuja
Olivia Nuti
Cameron Kemal
Darren Kang
Eugene Yuriditsky
James M. Horowitz
Raymond A. Pashun
To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
Case Reports in Cardiology
title To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_full To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_fullStr To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_full_unstemmed To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_short To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_sort to plex or not to plex for amiodarone induced thyrotoxicosis
url http://dx.doi.org/10.1155/2023/1563732
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