To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyro...
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Format: | Article |
Language: | English |
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Wiley
2023-01-01
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Series: | Case Reports in Cardiology |
Online Access: | http://dx.doi.org/10.1155/2023/1563732 |
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author | Tania Ahuja Olivia Nuti Cameron Kemal Darren Kang Eugene Yuriditsky James M. Horowitz Raymond A. Pashun |
author_facet | Tania Ahuja Olivia Nuti Cameron Kemal Darren Kang Eugene Yuriditsky James M. Horowitz Raymond A. Pashun |
author_sort | Tania Ahuja |
collection | DOAJ |
description | Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy. |
format | Article |
id | doaj-art-c41384990a1e496f9af1de9b46cbad5b |
institution | Kabale University |
issn | 2090-6412 |
language | English |
publishDate | 2023-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Cardiology |
spelling | doaj-art-c41384990a1e496f9af1de9b46cbad5b2025-02-03T06:47:46ZengWileyCase Reports in Cardiology2090-64122023-01-01202310.1155/2023/1563732To PLEX or Not to PLEX for Amiodarone-Induced ThyrotoxicosisTania Ahuja0Olivia Nuti1Cameron Kemal2Darren Kang3Eugene Yuriditsky4James M. Horowitz5Raymond A. Pashun6Department of MedicineDepartment of PharmacyDepartment of MedicineDepartment of Advanced Practice PractitionersDepartment of MedicineDepartment of MedicineDepartment of MedicineAmiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy.http://dx.doi.org/10.1155/2023/1563732 |
spellingShingle | Tania Ahuja Olivia Nuti Cameron Kemal Darren Kang Eugene Yuriditsky James M. Horowitz Raymond A. Pashun To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis Case Reports in Cardiology |
title | To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis |
title_full | To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis |
title_fullStr | To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis |
title_full_unstemmed | To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis |
title_short | To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis |
title_sort | to plex or not to plex for amiodarone induced thyrotoxicosis |
url | http://dx.doi.org/10.1155/2023/1563732 |
work_keys_str_mv | AT taniaahuja toplexornottoplexforamiodaroneinducedthyrotoxicosis AT olivianuti toplexornottoplexforamiodaroneinducedthyrotoxicosis AT cameronkemal toplexornottoplexforamiodaroneinducedthyrotoxicosis AT darrenkang toplexornottoplexforamiodaroneinducedthyrotoxicosis AT eugeneyuriditsky toplexornottoplexforamiodaroneinducedthyrotoxicosis AT jamesmhorowitz toplexornottoplexforamiodaroneinducedthyrotoxicosis AT raymondapashun toplexornottoplexforamiodaroneinducedthyrotoxicosis |