Perioperative and persistent opioid use after surgery: a scoping review
Persistent opioid use after surgery is a growing concern, with existing reviews lacking strong predictors beyond prior opioid use. This scoping review aimed to identify knowledge gaps for future research, particularly regarding the impact of the perioperative period (including preoperative, intraope...
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Elsevier
2025-06-01
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| Series: | BJA Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S277260962500036X |
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| author | Bader Almodibeg Jungwoo Kang Patrice Forget |
| author_facet | Bader Almodibeg Jungwoo Kang Patrice Forget |
| author_sort | Bader Almodibeg |
| collection | DOAJ |
| description | Persistent opioid use after surgery is a growing concern, with existing reviews lacking strong predictors beyond prior opioid use. This scoping review aimed to identify knowledge gaps for future research, particularly regarding the impact of the perioperative period (including preoperative, intraoperative, and postoperative) opioid use on persistent opioid use after surgery. A comprehensive database search of prospective studies explored the association between perioperative opioid use and persistent use in adults after surgery. From the 21 identified studies, we found a complex relationship between perioperative opioid use and persistent use. Preoperative opioid use correlated with persistent use, but the impact of intraoperative and short-term postoperative use remained unclear. Interestingly, postoperative prescriptions at 3 months predicted a higher risk of persistent use at 6 and 12 months. These findings highlight the need for further research to explore the mediating factors that increase the risk of persistent use among preoperative opioid users, along with the specific roles of intraoperative and postsurgical inpatient opioid consumption, and short-term postoperative opioid prescriptions (≤30 days). |
| format | Article |
| id | doaj-art-c406887c3f844aaca3c35cc42f4a309c |
| institution | OA Journals |
| issn | 2772-6096 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | BJA Open |
| spelling | doaj-art-c406887c3f844aaca3c35cc42f4a309c2025-08-20T01:55:30ZengElsevierBJA Open2772-60962025-06-011410041210.1016/j.bjao.2025.100412Perioperative and persistent opioid use after surgery: a scoping reviewBader Almodibeg0Jungwoo Kang1Patrice Forget2Anaesthesia and Operation Technology Department, King Khalid University, College of Applied Medical Sciences, Khamis Mushait, Asir, Saudi Arabia; Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen - School of Medicine, Medical Sciences and Nutrition, Institute of Applied Health Sciences, Foresterhill Health Campus, Aberdeen, UK; Pain and Opioids after Surgery (PANDOS) European Society of Anaesthesiology and Intensive Care (ID ESAIC_RG_PAND) Research Group, Brussels, Belgium; Corresponding author. Anaesthesia and Operation Technology Department, King Khalid University, College of Applied Medical Sciences, Khamis Mushait, Asir, Saudi Arabia.Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen - School of Medicine, Medical Sciences and Nutrition, Institute of Applied Health Sciences, Foresterhill Health Campus, Aberdeen, UKAberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen - School of Medicine, Medical Sciences and Nutrition, Institute of Applied Health Sciences, Foresterhill Health Campus, Aberdeen, UK; Pain and Opioids after Surgery (PANDOS) European Society of Anaesthesiology and Intensive Care (ID ESAIC_RG_PAND) Research Group, Brussels, Belgium; Department of Anaesthesia, NHS Grampian, Aberdeen, UK; IMAGINE UR UM 103, Montpellier University, Anesthesia Critical Care, Emergency and Pain Medicine Division, Nîmes University Hospital, Nîmes, FrancePersistent opioid use after surgery is a growing concern, with existing reviews lacking strong predictors beyond prior opioid use. This scoping review aimed to identify knowledge gaps for future research, particularly regarding the impact of the perioperative period (including preoperative, intraoperative, and postoperative) opioid use on persistent opioid use after surgery. A comprehensive database search of prospective studies explored the association between perioperative opioid use and persistent use in adults after surgery. From the 21 identified studies, we found a complex relationship between perioperative opioid use and persistent use. Preoperative opioid use correlated with persistent use, but the impact of intraoperative and short-term postoperative use remained unclear. Interestingly, postoperative prescriptions at 3 months predicted a higher risk of persistent use at 6 and 12 months. These findings highlight the need for further research to explore the mediating factors that increase the risk of persistent use among preoperative opioid users, along with the specific roles of intraoperative and postsurgical inpatient opioid consumption, and short-term postoperative opioid prescriptions (≤30 days).http://www.sciencedirect.com/science/article/pii/S277260962500036Xintraoperative opioidopioid crisisperioperative opioidpersistent opioidpostoperative opioidpreoperative opioid |
| spellingShingle | Bader Almodibeg Jungwoo Kang Patrice Forget Perioperative and persistent opioid use after surgery: a scoping review BJA Open intraoperative opioid opioid crisis perioperative opioid persistent opioid postoperative opioid preoperative opioid |
| title | Perioperative and persistent opioid use after surgery: a scoping review |
| title_full | Perioperative and persistent opioid use after surgery: a scoping review |
| title_fullStr | Perioperative and persistent opioid use after surgery: a scoping review |
| title_full_unstemmed | Perioperative and persistent opioid use after surgery: a scoping review |
| title_short | Perioperative and persistent opioid use after surgery: a scoping review |
| title_sort | perioperative and persistent opioid use after surgery a scoping review |
| topic | intraoperative opioid opioid crisis perioperative opioid persistent opioid postoperative opioid preoperative opioid |
| url | http://www.sciencedirect.com/science/article/pii/S277260962500036X |
| work_keys_str_mv | AT baderalmodibeg perioperativeandpersistentopioiduseaftersurgeryascopingreview AT jungwookang perioperativeandpersistentopioiduseaftersurgeryascopingreview AT patriceforget perioperativeandpersistentopioiduseaftersurgeryascopingreview |