Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations
Background: pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) improves health-related quality of life (QoL). This study compares QoL improvement after radiofrequency ablation (RF) and cryoballoon ablation (cryo) and assesses additional ablations’ role in QoL improvement. Method...
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2024-11-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| author | Ibrahim Antoun Ahmed I. Kotb Zakkariya Vali Ahmed Abdelrazik Ivelin Koev Kassem Safwan Edward Y. M. Lau Riyaz Somani Ghulam André Ng |
| author_facet | Ibrahim Antoun Ahmed I. Kotb Zakkariya Vali Ahmed Abdelrazik Ivelin Koev Kassem Safwan Edward Y. M. Lau Riyaz Somani Ghulam André Ng |
| author_sort | Ibrahim Antoun |
| collection | DOAJ |
| description | Background: pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) improves health-related quality of life (QoL). This study compares QoL improvement after radiofrequency ablation (RF) and cryoballoon ablation (cryo) and assesses additional ablations’ role in QoL improvement. Methods: we evaluated the QoL of consecutive patients with first-time RF and cryo for PAF between January 2017 and June 2019. A combined EQ-VAS, AFEQT, and EQ-5D-3L paper questionnaire was sent to patients at baseline, 12, and 30 months after the procedure. Procedure and patient details were collected from medical notes. Results: the analysis included 207 patients, of which 127 (61%) had RF and 144 (70%) were males. RF patients had more additional ablations (52 [41%] versus 22 [28%], <i>p</i> = 0.01). There was a significant improvement from baseline to 12 months post-RF in AFEQT (43 ± 9 to 83 ± 7.8, <i>p</i> < 0.001), EQ-5D-3L (−0.01 ± 0.01 to 1.1 ± 0.02, <i>p</i> < 0.001), and EQ-VAS (51 ± 8 to 77 ± 13, <i>p</i> = 0.01). Similarly, an improvement at 12 months was observed after cryo in AFEQT (55 ± 11 to 77 ± 9, <i>p</i> < 0.001), EQ-5D-3L (−0.04 ± 0.03 to 1.3 ± 0.03, <i>p</i> < 0.001), and EQ-VAS (56 ± 7 to 85 ± 9, <i>p</i> = 0.01). QoL improvement was similar between RF and cryo. Additional ablations provided no additional QoL improvement compared to patients with PVI alone. Conclusions: Patients undergoing first-time PVI for PAF, RF, and cryo showed similar QoL improvement at 12 months, which was sustained at 30 months. Additional ablations did not provide further QoL benefits. |
| format | Article |
| id | doaj-art-c405c1ef9a78414baf9c37cf7e6c25d7 |
| institution | DOAJ |
| issn | 2308-3425 |
| language | English |
| publishDate | 2024-11-01 |
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| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj-art-c405c1ef9a78414baf9c37cf7e6c25d72025-08-20T02:53:41ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252024-11-01111238510.3390/jcdd11120385Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional AblationsIbrahim Antoun0Ahmed I. Kotb1Zakkariya Vali2Ahmed Abdelrazik3Ivelin Koev4Kassem Safwan5Edward Y. M. Lau6Riyaz Somani7Ghulam André Ng8Department of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UKDepartment of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE3 9QP, UKDepartment of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UKDepartment of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE3 9QP, UKDepartment of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE3 9QP, UKDepartment of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE3 9QP, UKDepartment of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UKDepartment of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UKDepartment of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UKBackground: pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) improves health-related quality of life (QoL). This study compares QoL improvement after radiofrequency ablation (RF) and cryoballoon ablation (cryo) and assesses additional ablations’ role in QoL improvement. Methods: we evaluated the QoL of consecutive patients with first-time RF and cryo for PAF between January 2017 and June 2019. A combined EQ-VAS, AFEQT, and EQ-5D-3L paper questionnaire was sent to patients at baseline, 12, and 30 months after the procedure. Procedure and patient details were collected from medical notes. Results: the analysis included 207 patients, of which 127 (61%) had RF and 144 (70%) were males. RF patients had more additional ablations (52 [41%] versus 22 [28%], <i>p</i> = 0.01). There was a significant improvement from baseline to 12 months post-RF in AFEQT (43 ± 9 to 83 ± 7.8, <i>p</i> < 0.001), EQ-5D-3L (−0.01 ± 0.01 to 1.1 ± 0.02, <i>p</i> < 0.001), and EQ-VAS (51 ± 8 to 77 ± 13, <i>p</i> = 0.01). Similarly, an improvement at 12 months was observed after cryo in AFEQT (55 ± 11 to 77 ± 9, <i>p</i> < 0.001), EQ-5D-3L (−0.04 ± 0.03 to 1.3 ± 0.03, <i>p</i> < 0.001), and EQ-VAS (56 ± 7 to 85 ± 9, <i>p</i> = 0.01). QoL improvement was similar between RF and cryo. Additional ablations provided no additional QoL improvement compared to patients with PVI alone. Conclusions: Patients undergoing first-time PVI for PAF, RF, and cryo showed similar QoL improvement at 12 months, which was sustained at 30 months. Additional ablations did not provide further QoL benefits.https://www.mdpi.com/2308-3425/11/12/385atrial fibrillationcatheter ablationquality of liferadiofrequency ablationcryoballoon ablation |
| spellingShingle | Ibrahim Antoun Ahmed I. Kotb Zakkariya Vali Ahmed Abdelrazik Ivelin Koev Kassem Safwan Edward Y. M. Lau Riyaz Somani Ghulam André Ng Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations Journal of Cardiovascular Development and Disease atrial fibrillation catheter ablation quality of life radiofrequency ablation cryoballoon ablation |
| title | Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations |
| title_full | Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations |
| title_fullStr | Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations |
| title_full_unstemmed | Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations |
| title_short | Long-Term Patient-Reported Outcomes After Radiofrequency Ablation and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation: The Effect of Additional Ablations |
| title_sort | long term patient reported outcomes after radiofrequency ablation and cryoballoon ablation for paroxysmal atrial fibrillation the effect of additional ablations |
| topic | atrial fibrillation catheter ablation quality of life radiofrequency ablation cryoballoon ablation |
| url | https://www.mdpi.com/2308-3425/11/12/385 |
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