Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Advances in Virology |
| Online Access: | http://dx.doi.org/10.1155/2011/797820 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560829975756800 |
|---|---|
| author | Krista A. Delviks-Frankenberry Chawaree Chaipan Rachel Bagni Kathleen Wyvill Robert Yarchoan Vinay K. Pathak |
| author_facet | Krista A. Delviks-Frankenberry Chawaree Chaipan Rachel Bagni Kathleen Wyvill Robert Yarchoan Vinay K. Pathak |
| author_sort | Krista A. Delviks-Frankenberry |
| collection | DOAJ |
| description | Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas. |
| format | Article |
| id | doaj-art-c3fe744fee1c4a4298fd2272e9702c4d |
| institution | Kabale University |
| issn | 1687-8639 1687-8647 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Virology |
| spelling | doaj-art-c3fe744fee1c4a4298fd2272e9702c4d2025-02-03T01:26:42ZengWileyAdvances in Virology1687-86391687-86472011-01-01201110.1155/2011/797820797820Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma PatientsKrista A. Delviks-Frankenberry0Chawaree Chaipan1Rachel Bagni2Kathleen Wyvill3Robert Yarchoan4Vinay K. Pathak5Viral Mutation Section, HIV Drug Resistance Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USAViral Mutation Section, HIV Drug Resistance Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USAProtein Expression Laboratory, SAIC-Frederick Inc., NCI-Frederick, Frederick, MD 21702, USAHIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USAHIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USAViral Mutation Section, HIV Drug Resistance Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USAXenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas.http://dx.doi.org/10.1155/2011/797820 |
| spellingShingle | Krista A. Delviks-Frankenberry Chawaree Chaipan Rachel Bagni Kathleen Wyvill Robert Yarchoan Vinay K. Pathak Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients Advances in Virology |
| title | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
| title_full | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
| title_fullStr | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
| title_full_unstemmed | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
| title_short | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
| title_sort | lack of detection of xenotropic murine leukemia virus related virus in hiv 1 lymphoma patients |
| url | http://dx.doi.org/10.1155/2011/797820 |
| work_keys_str_mv | AT kristaadelviksfrankenberry lackofdetectionofxenotropicmurineleukemiavirusrelatedvirusinhiv1lymphomapatients AT chawareechaipan lackofdetectionofxenotropicmurineleukemiavirusrelatedvirusinhiv1lymphomapatients AT rachelbagni lackofdetectionofxenotropicmurineleukemiavirusrelatedvirusinhiv1lymphomapatients AT kathleenwyvill lackofdetectionofxenotropicmurineleukemiavirusrelatedvirusinhiv1lymphomapatients AT robertyarchoan lackofdetectionofxenotropicmurineleukemiavirusrelatedvirusinhiv1lymphomapatients AT vinaykpathak lackofdetectionofxenotropicmurineleukemiavirusrelatedvirusinhiv1lymphomapatients |