Change detection in the dynamics of an intracellular protein synthesis model using nonlinear Kalman filtering

A method for early diagnosis of parametric changes in intracellular protein synthesis models (e.g. the p53 protein - mdm2 inhibitor model) is developed with the use of a nonlinear Kalman Filtering approach (Derivative-free nonlinear Kalman Filter) and of statistical change detection methods. The int...

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Bibliographic Details
Main Authors: Gerasimos G. Rigatos, Efthymia G. Rigatou, Jean Daniel Djida
Format: Article
Language:English
Published: AIMS Press 2015-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1017
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